The importance of Charlsonovog comorbidity index in assessing multiyear survival of patients with prostate cancer

Nikola Kolarovic ,
Nikola Kolarovic
Bora Cvetkovic ,
Bora Cvetkovic
Dragan Grebenarovic ,
Dragan Grebenarovic
Sasa Mazibrada ,
Sasa Mazibrada
Goran Potpara ,
Goran Potpara
Aleksandar Argirovic ,
Aleksandar Argirovic
Aleksandar Antic ,
Aleksandar Antic
Vuk Aleksic ,
Vuk Aleksic
Perica Jockic
Perica Jockic

Published: 01.12.2015.

Biochemistry

Volume 32, Issue 1 (2016)

pp. 1392-1396;

https://doi.org/10.5937/matmed1601392k

Abstract

Prostate cancer is the second most common cause of cancer mortality in men population. Multifactorial etiology, unpredictable course and outcome of the disease put survival determining factors of disease in the spotlight. One of new survival prognostic factors is Charlson Comorbidity Index – CCI. We presented basic characteristics of CCI, literature review regarding the CCI, as well as advantages and disadvantages of this index. CCI represents optimal balance between ease of use and prognostic capabilities. CCI value significantly contributes to better assessment of the long-term survival and the selection of appropriate cancer therapy.

Keywords

References

1.
Boyle P, Ferlay J. Cancer incidence and mortality in Europe. Ann Oncol. 2004;(3):481–8.
2.
Jemal A, Siegel R, Ward E. Cancer statistics. 2008;(2):71–96.
3.
Charlson M, Pompei P, Ales K, Mackenzie C. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. Journal of Chronic Diseases. 1987;(5):373–83.
4.
Kaplan M, Feinstein A. The importance of classifying initial comorbidity in evaluating the outcome of diabetes mellitus. J Chronic Dis. 1974;387–404.
5.
Valderas S, Jose M, Starfild B. Defining comorbidity: Implications for Understanding Health and Health Services. Annals of Family Medicine. 2009;(4):357–63.

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