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Primary endobronchial synovial sarcoma
Institute for Pulmonary Diseases of Vojvodina, Faculty of Medicine, University of Novi Sad , Novi Sad , Serbia
Institute for Pulmonary Diseases of Vojvodina, Faculty of Medicine, University of Novi Sad , Novi Sad , Serbia
Institute for Cardiovascular Diseases of Vojvodina, Faculty of Medicine, University of Novi Sad , Novi Sad , Serbia
Oncology Institute of Vojvodina, Faculty of Medicine, University of Novi Sad , Novi Sad , Serbia
Institute for Pulmonary Diseases of Vojvodina, Faculty of Medicine, University of Novi Sad , Novi Sad , Serbia
Institute for Pulmonary Diseases of Vojvodina, Faculty of Medicine, University of Novi Sad , Novi Sad , Serbia
Institute for Pulmonary Diseases of Vojvodina, Faculty of Medicine, University of Novi Sad , Novi Sad , Serbia
Published: 01.04.2018.
Volume 34, Issue 1 (2018)
pp. 46-46;
Abstract
Aim: We present the case of a woman with endobronchial pulmonary synovial sarcoma. Introduction: Primary pulmonary synovial sarcoma is an extremely rare tumor that has the same histomorphological characteristics and chromosomal translocations as the synovial sarcoma of soft tissue origin. Material and Methods: A woman aged 58 years, the smoker, without the current symptoms of the disease, came to our institution because of the nodus that was seen on the CT chest. The polip (26 mm) was located in the lumen of the lower right lobar bronchus. The mediastinal and hilar lymph nodes were not increased. The radiological examination was done as part of a routine control after the meningeoma surgery three years ago. Right lower lobectomy and resection of regional lymph nodes were performed. Results: By a macroscopic examination, in the lumen of the bronchus for the lower right lobes, a clearly limited, nonencapsulated, grayish-white node of 2.6 x 2.6 x 1 cm was found. Histologically, the tumor was showed interweaving fascicular uniform spindle cell with ovoid, pale staining nuclei, and inconspicuous nucleoli, scant cytoplasm and the cell borders indistinct. Immunohistochemical tumor cells were positive for CD99, bcl2 and vimentin. Surgical margins and regional lymph nodes were not affected. A detailed clinical and radiological examination confirmed the primary lung origin of the diagnosed synovial sarcoma. A year after surgery the patient feels good. Conclusion: Morphological and immunohistochemical analysis with detailed clinical and radiological examination confirms the primary lung origin of synovial sarcoma
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