Postoji relativno malo podataka u literaturi koji imaju za cilj procenu korelacije između kvaliteta ishrane i simptoma donjih partija urotrakta (SDPU). Cilj ove studije je da proceni povezanost izmedju kvaliteta ishrane i SDPU. Naša hipoteza je bila da je izbalansirana zdrava ishrana udružena sa manjom učestalošću SDPU. Studija obuhvata 852 pacijenata starosti >40 godina od kojih je 724 (85%) kompletiralo urinarni upitnik. Primenjena je bivarijantna analiza da se ispita stepen SDPU kod pacijenata sa dobrom i lošom ishranom. Multivarijantna regresiona analiza je primenjena da se proceni uticaj demografskih faktora kod pacijenata sa ili bez SDPU u zavisnosti odgodina starosti, pušenja, dijabetesa, konzumiranja alkohola, gojaznosti i fizičke aktivnosti. Pošto smo isključili iz analize 31 pacijenta sa karcinomom prostate, naša studija je obuhvatala 693 muškaraca od kojih je 139 (20%) imalo najmanje jedan simptom indikativan za SDPU (63 iritativne, 46 opstruktivne i 30 oba simptoma). Veća verovatnoća za pojavu SDPU je postojala kod seoske populacije (p<0.0001), nepušača (p<0.0001), dijabetičara (P<0.0001), starijih muškaraca (p<0.0001), sa višim PSA (p<0.0001) i dijagnozom uvećanja prostate (p<0.0001). Umerena i intenzivna fizička aktivnost i unos alkohola su bili češće zastupljeni kod muškaraca bez SDPU (p<0.0001). Nadjena je veća učestalost SDPU kod muškaraca sa malim unosom mlečnih proizvoda (22.4%:16.4%) (p=0.0013), oskudnim unosom proteina (24.6%:17.9%)(p=0.012), generalno lošom ishranom (28.2%:17.8%) (p=0.012) i malom raznolikošću ishrane (26.1%:17.6%) (p=0.001). Multivarijantna analiza je pokazala da nezdrava ishrana, seoska populacija i stariji muškarciimaju veći rizik za pojavu SDPU, dok je unos alkohola imao protektivno dejstvo na SDPU.
Ulrich P, Lutgendorf S, Leserman J. Stress, hostility, and disease parameters of benign prostatic hyperplasia. Psychosom Med. 2005;476–82.
2.
Rohrmann S, Smit E, Giovannucci E. Association between markers of the metabolic syndrome and lower urinary tract symptoms in the Third National Health and Nutrition Examination Survey (NHANES III). Int J Obes. 2005;310–6.
3.
Orsini N, Khani R, Anderson B, S. Long-term physical activity and lower urinary tract symptoms in men. J Urol. 2006;1546–50.
4.
Mcvary K, Rademaker A, Lloyd G. Autonomic nervous system overactivity in men with lower urinary tract symptoms secondary to benign prostatic hyperplasia. J Urol. 2005;1327–33.
5.
St, Saurer J, Jacobson D, Mcgree M. Association between longitudinal changes in serum estrogen, testosterone, and bioavailable testosterone and changes in benign urologic outcomes. Am J Epidemiol. 2011;787–96.
6.
Rohrmann S, Nelson W, Rifai N. Serum, sex steroid hormones and lower urinary tract symptomes in Third National Health and Nutrition Examination Survey (NHANES III). Urology. 2007;708–13.
7.
Rohramnn S, Giovannucci E, Willet W. Fruit and vegetable consumption, intake of micronutrutients, and benign prostatic hyperplasia in US men. Am J Clin Nutr. 2007;523–9.
8.
Kristal A, Arnold K, Schenk J. Dietary patterns, supplement use, and the risk of symptomatic benign prostatic hyperplasia. Am J Epidemiol. 2008;925–34.
9.
Chyon P, Nomura A, Stimmermann G. A prospective study of alcohol, diet and other lifestyle factors in relation to obstructive uropathy. Prostate. 1993;253–64.
10.
Rohrmann S, Giovannucci E, Willet W. Fruit and vegetable consumption, intake of micronutrutients, and benign prostatic hyperplasia in US men. Prostate. 2007;523–9.
11.
Rohrmann S, Crespo C, Weber J. Association of cigerette smoking, alcohol consumption and physical activity with lower urinary tract symptom s in older American men: findings from the Third National Health and Nutrition Examination Survey. BJU Int. 2005;77–82.
12.
Parsons J. Lifestyle factors, benign prostatic hyperplasia and lower tract symptoms. Curr Opin Urol. 2001;1–4.
13.
Bravi S, Bosetti C, Maso D, L. Macronutritients, fatty acids, cholesterol, and risk of benign prostatic hyperplasia. Urology. 2006;1205–11.
14.
Ambrosini G, De Klerk N, Mackerras D. Dietary patterns and surgically treated benign prostatic hyperplasia: a case control study in Western Australia. BJU Int. 2008;853–60.
15.
Bravi S, Bosetti C, Maso D, L. Food groups and risk of benign prostatic hyperplasia. Urology. 2006;73–9.
16.
Mccullough M, Feskanich D, Rimm E. Adherence to the dietary guidelines for Americans and risk of major chronic disease in men. Am J Clin Nutr. 2000;1223–31.
17.
Marzo D, Coffey A, Nelson D, W. New concepts in tissue specifity for prostate cancer and benign prostatic hyperplasia. Urology. 1999;29–39.
18.
Suzuki S, Platz E, Kawachi I. Intakes of energy and macronutritients and the risk of benign prostatic hyperplasia. Am J Clin Nutr. 2002;689–97.
19.
Appel L, Champagne C, Harsha D. Effects of comprehensive lifestyle modification of blood pressure control: main results of the PREMIER clinical trial. jAMA. 2003;2083–93.
20.
Weihna Z, Makela S, Anderson L. A role for estrogen receptor beta in the regulation of growth of the ventral prostate. Proc Natl Acad Sci. 2001;6330–5.
21.
Fowke J, Munro H, Signorella Lb. Association between socioeconomic status (SES) and lower urinary tract symptoms (LUTS): severity between black and white men. J Ger Intern Med. 2011;(11):1305–10.
22.
Dramon N, Drenowski A. Corresponing author: Djordje Argirović Outpatient Clinic "Argirović. Am J Clin Nutr. 2008;1107–17.
23.
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