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Presepsin u akutnim i hroničnim poremećajima bubrežne funkcije

Zoran Gluvić ,
Zoran Gluvić
Contact Zoran Gluvić

Odeljenje internističke intenzivne nege i Služba endokrinologije, 1KBC Zemun, Klinika za internu medicinu Serbia

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Bojan Mitrović ,
Bojan Mitrović

Odeljenje internističke intenzivne nege i Služba endokrinologije, 1KBC Zemun, Klinika za internu medicinu Serbia

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Andrijana Kulić ,
Andrijana Kulić

Služba za transfuziologiju, KBC Zemun

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Ana Strugar ,
Ana Strugar

Služba za transfuziologiju, KBC Zemun

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Vesna Libek
Vesna Libek

Služba za transfuziologiju, KBC Zemun

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Published: 01.12.2017.

Volume 33, Issue 3 (2017)

pp. 1571-1573;

https://doi.org/10.5937/MatMed1703571G

Abstract

Za postavljanje dijagnoze sepse, najpouzdanije je određivanje PSP u kombinaciji sa drugim markerima sistemske infekcije. Pojedinačno merenje je često bez značaja, tako da je kontinuirano merenje u vremenu, sa trendovima pada ili porasta nivoa markera sistemske infekcije, daleko informativnije. Nivo PSP značajno zavisi od GFR. Kod obolelih od ABI, PSP je solidan pokazatelj sistemske infekcije do težih i prologiranih stadijuma ABI. Kod obolelih od HBI, tumačenje vrednosti PSP je veoma spekulativno, te postoji potreba za definisanjem novihcut-off vrednosti za PSP kod ovih bolesnika. Kod oblelih pod tretmanom HD, pokazan je različit klirens PSP sa različitim dijaliznim membranama. Svakako, nivo PSP se po HD vraća na pređašnji nivo, koji je inače povišen.

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