The team management of patient suffered of acute severe dyslipidaemic pancreatitis - the experience of one tertiary health centre

Marija Popin-Tarić ,
Marija Popin-Tarić

Department of Geriatrics, Clinic for Internal Medicine, KBC Zemun Serbia

Zoran Gluvić ,
Zoran Gluvić

Department of Endocrinology, Clinic for Internal Medicine, KBC Zemun Serbia

Bojan Mitrović ,
Bojan Mitrović

Department of Endocrinology, Clinic for Internal Medicine, KBC Zemun Serbia

Vladimir Samardžić ,
Vladimir Samardžić

Department of Endocrinology, Clinic for Internal Medicine, KBC Zemun Serbia

Milena Lačković ,
Milena Lačković

Department of Endocrinology, Clinic for Internal Medicine, KBC Zemun Serbia

Aleksandar Stanojević ,
Aleksandar Stanojević

Department of Gastroenterology, Clinic for Internal Medicine, KBC Zemun Serbia

Adrijana Kulić ,
Adrijana Kulić

Department of Transfusion, KBC Zemun Serbia

Vesna Libek ,
Vesna Libek

Department of Transfusion, KBC Zemun Serbia

Ivana Resanović ,
Ivana Resanović

Laboratory for Molecular Genetics and Radiobiology, Institute for Nuclear Sciences “Vinča”, University of Belgrade , Belgrade , Serbia

Esma R. Isenović
Esma R. Isenović

Laboratory for Molecular Genetics and Radiobiology, Institute for Nuclear Sciences “Vinča”, University of Belgrade , Belgrade , Serbia

Published: 01.12.2017.

Volume 33, Issue 3 (2017)

pp. 1557-1562;

Abstract

This article presents a case of patient with acute and complicated dyslipidaemic pancreatitis, managed by team, consisted of the endocrinologists, gastroenterologists and transfusiologists. Dyslipidaemia, predominantly type IV, is a common cause of acute pancreatitis in young patients, especially in the cases of poor compliance (irregular taking of recommended fibrates and failure to comply with the dietary regime). The treatment of acute pancreatitis, regardless of the aetiology, is due to the severity of the condition, the complexity of the treatment, and the monitoring of patients, in the Intensive Care Units. In cases where dyslipidaemia is the cause of acute pancreatitis, in the context of acute care, a therapeutic plasma exchange is often performed. It rapidly and significantly corrects lipid levels, primarily triglycerides. Therapeutic plasma exchange requires the activity of transfusiology team, which are often unavailable in smaller hospitals.

 

Keywords

References

1.
Harper SJF, Cheslyn-Curtis S. Acute pancreatitis. *Annals of Clinical Biochemistry. 48:23–37.
2.
Toskes PP. Hyperlipidemic pancreatitis. *Gastroenterology Clinics of North America. 19:783–91.
3.
Criddle DN, Murphy J, Fistetto G, Barrow S, Tepikin AV, Neoptolemos JP, et al. Fatty acids ethyl esters cause pancreatic calcium toxicity via inositol triphosphate receptors and loss of ATP synthesis. *Gastroenterology. 130:781–93.
4.
Tsuang W, Navaneethan U, Ruiz L, Palascak JB, Gelrud A. Hypertriglyceridemic pancreatitis: presentation and management. *American Journal of Gastroenterology. 104:984–91.
5.
Ewald N, Hardt PD, Kloer HU. Severe hypertriglyceridemia and pancreatitis: presentation and management. *Current Opinion in Lipidology. 20:497–504.
6.
Hamada S, Masamune A, Shimosegawa T. Management of acute pancreatitis in Japan: analysis of nationwide epidemiological survey. *World Journal of Gastroenterology. 22:6335–44.
7.
Iyengar SS, Puri SS, Narasingan SN, Nair DR, Mehta V, Mohan JC, et al. Lipid Association of India (LAI) expert consensus statement on management of dyslipidaemia in Indians: part 2. *Clinical Lipidology. 12:56–109.
8.
Stefanutti C, Giacomo S, Vivenzio A, Labbadia G, Mazza F, D’Alessandri G, et al. Therapeutic plasma exchange in patients with severe hypertriglyceridemia: a multicenter study. *Artificial Organs. 33*(12:1096–102.
9.
Gavva C, Sarode R, Agrawal D, Burner J. Therapeutic plasma exchange for hypertriglyceridemia induced pancreatitis: A rapid and practical approach. *Transfusion and Apheresis Science. 54*(1:99–102.
10.
Brecher M. E.
11.
Schwartz J, Padmanabhan A, Aqui N, Balogun RA, Connelly-Smith L, Delaney M, et al. Guidelines on the use of therapeutic apheresis in clinical practice—evidence-based approach from the Writing Committee of the American Society for Apheresis. The Seventh Special Issue *Journal of Clinical Apheresis. 31*(3:149–62.

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