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OrIGINaLNI radOVI OrIGINaL arTICLEs Gliomi mozga kod starijih pacijenata: astrocitomi, oligodendrogliomi i ependimomi

Radomir Benovic ,
Radomir Benovic
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Nenad Zivkovic ,
Nenad Zivkovic
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Marko Samardzic ,
Marko Samardzic
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Igor Popovic ,
Igor Popovic
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Jasmina Djukic
Jasmina Djukic
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Published: 01.12.2010.

Biochemistry

Volume 27, Issue 3 (2011)

pp. 345-351;

https://doi.org/10.5937/matmed1103345b

Abstract

Maligni astrocitomi su najčešći primarni tumori mozga kod odraslih i čine 2% od ukupnog broja malignih tumora. Glioblastom multiforme (GBM ) je visoko specifičan za stariju populaciju dok je kod mlađih od 14 godina izuzetno redak. GBM je malo zastupljeniji kod muškog pola nego kod ženskog u odnosu 1,6. Ovom retrospektivnom studijom obuhvaćeno je 183 pacijenata sa dijagnozom tumora mozga, operativno lečenih na odeljenju neurohirurgije KBC Zemun. U grupi mikstnih glioma postoji veća učestalost u odnosu na ostale tumore, kao i veća zastupljenost kod muškog pola 57 (60,6%), u odnosu na žensku populaciju 37 (39,4%). U odnosu na histološki tip analizirani su slučajevi koji su operisani i reoperisani (dijagnoza potvrđena PH nalazom). Od ukupno 175 operisanih i reoperisanih 40 (23%) su astrocitomi, 35 (20%) oligodendrogliomi, 94 (53,3%) multiformni glioblastomi (mikstni gliomi), i 6 (3,3%) ependimomi. Tipična lokalizacija astrocitoma i multiformnih glioblastoma je unutar temporalnog lobusa. Oligodendrogliomi su najčešće bili smešteni u prednjoj trećini velikog mozga, sa upadljivo najčešćim zahvatanjem frontalnih regiona.

Keywords

gliomi,

tumori mozga gliomas,

brain tumors

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