Breast cysts are the most common benign changes at women aged 35 to 50 years old. Usually there isn’t highest risk for breast cancer in women with cystic changes, but in the rare cases cancer can be found in association with a cyst. We reported two patients aged 33 and 45 years old. Both of them had breast cystic changes. We performed Fine Needle Aspiration (FNA) with cytological examination of the aspirated content, the breast ultrasound examination and mammography for second patient. Cysts were surgically removed and sent to the final histopathological verification. Patient 33 years old was diagnosed medullary breast cancer and undergone axillary dissection and breast sentinel node biopsy (SNB) with histopathological (HP) and immunohistochemical (IHC) findings, after that patient was treated with adjuvant chemotherapy. In patient 44 years old was diagnosed mucinous breast cancer, performed partial breast resection with axillary dissection and applied adjuvant hormonal therapy. Radiotherapy was conducted on both patients and they were followed for 3 years by a regional oncologic dispensary. Although malignant cells wasn’t find by cytological examination we have to be careful because in the wall of the cyst may be malignant cells, so histopathological (HP) and immunohistochemical (IHC) findings are the most relevant diagnostic procedures. Primary treatment of breast cancer is surgery, but important role in management have postoperative radiotherapy, chemotrerapy and hormonal therapy. Survival depends on the size, type of tumor and affected lymph nodes. Prognostic parameters which should be considered are: menopausal status, tumor size, tumor location, lymph node status, tumor type, nuclear grade, histological grade,
hormone receptors and tumor markers.

Na početku 21. veka, u vremenu društveno-političkih i ekonomskih previranja, u tadašnjoj Jugoslaviji nije bilo organizovanih naučnih i edukativnih aktivnosti u oblasti ehokardiografije. Zahvaljujući entuzijazmu nekoliko srpskih kardiologa, koji su prepoznali potrebu za promenom, aprila 2001. godine u Beogradu je osnovano ehokardiografsko udruženje, sa ciljem da postavi standarde ehokardiografskog pregleda, podrži naučne aktivnosti u oblasti ehokardiografije i osnaži saradnju sa međunarodnim ehokardiografskim organizacijama. Nakon raspada bivše Jugoslavije, prvobitan naziv «Jugoslovensko ehokardiografsko udruženje» (YUECHO), 2006. godine promenjen je u Ehokardiografsko udruženje Srbije (ECHOS).

The purpose of this study was to evaluate the spectrum of the Waldeyer’s ring tumor pathology. Waldeyer’s ring is a ringed arrangement of lymphoid tissue that surrounds nasopharynx and oropharynx. It consists of a pharyngeal tonsil, two tubal tonsils, two palatinal tonsils in the oropharynx, and lingual tonsil. The tonsils are made of heterogeneous tissues, therefore inside the tonsils proliferations could be neoplastic or reactive nature. The participants in our retrospective research were one thousand one hundred thirty patients with histopathology report of tumors of the Waldeyer’s ring. Seven hundred eleven where male and four hundred nineteen were female. The research was conducted at the Clinic for Otorhinolaryngology and Maxillofacial Surgery of the Clinical Center of Serbia from January 1, 2007 to December 31, 2017. The collected data was analyzed by descriptive and analytical statistic methods. It was found that the highest percent of participants developed reactive follicular hyperplasia (51,2%), 25.9% percent squamocellular carcinoma, 8.4% undifferentiated non keratinizing nasopharyngeal carcinoma, and 8.0% nonHodgkin lymphoma. The most malignant tumors were found among male participants over 60 years of age. The majority of malignant tumors grew in oropharynx. The most common tumor was squamous cell carcinoma.

The aim of the study was to investigate the degree of exposure to the health risk of the user by using a medical prescription reading goggles, which are classified as low risk, and whether the data from the package leaflet are correctly applied. Medical devices are instruments, apparatus, materials and other products intended to be used for humans and which do not achieve its basic purpose on the basis of pharmacological, immunological or metabolic activity, but are used alone or in combination, including the software required for proper use. Depending on the categories to which they belong, medical devices have greater or lesser risk of adverse health effects on patients. Medical devices are classified to classes according to the degree of risk for the user ranging from low risk to high risk. Research was conducted in retail stores: pharmacies, optical stores and facilities for selling consumer goods. The survey questionnaire methodology collected data on habits of customers - users of diopter reading glasses. The survey was conducted among the masters of pharmacies, opticians and retailers in the period from March to June 2019. Twenty-five facilities were included in the survey in the area of Tuzla, Sarajevo and Zenica.Statistical data processing was done in Microsoft Excel. Study showed that 35% of the respondents answered that patients visited ophthalmologists and brought medical report with needed corrective diopter, while significantly larger number of respondents – 65% answered that patients didn’t visit ophthalmologists and didn’t have a medical report with needed corrective diopter. Research has shown that 73.75% of patients don’t read the instructions for use, while only 26.25% of patients read instructions for use.

The aim of this case report was to review the therapeutic effect of therapeutic plasma exchange in the treatment of retrobulbar neuritis in relation to its side effects, in the absence of the desired therapeutic response to previously applied immunomodulatory therapy, as a justification of therapeutic plasma exchange in the treatment of patients suffering from central nervous system demyelinating diseases. Optic neuritis is an inflammatory optic nerve lesion that may lead to partial or complete loss of vision. Therapeutic plasma exchange was performed on the SPECTRA OPTIA apheresis apparatus, according to a predefined disease diagnosis (RN), which according to the 2016 AFSA criteria belongs to the III category of disease in which apheresis is accepted as the second line of treatment. Three procedures were analyzed and an average of 5050ml of blood was processed. In conclusion, this therapeutic method is absolutely justified, with the appropriate prior preparation of the patient.