According to the relevant investigations during past decade there is a great increase of malignant skin tumors. By this research we tried to investigate this hypothesis in domestic population and present complicated reconstructive procedure. In this research were included 591 patients with melanomas and carcinomas of head and neck, who were surgically treated at our clinic from 2000. to 2010. Results of this research showed that 50 patients had melanoma and 541 carcinomas of skin. We have found that men are four times more affected by skin facial carcinomas than women. 62% patients with squamous cell carcinoma, who were primary surgically treated, survived more than 5 years. On other hand, 85% patients with basal cell carcinomas survived more than 5 years.

Sposobnost organizma da zaustavi krvarenje iz oštećenog krvnog suda je neophoda za preživljavanje pacijenta.Isto tako,veliki uticaj ima i sposobnost organizma u regulisanju različitih procesa u koagulaciji krvi,čime
se može sprečiti nastanak tromboza i mogućih fatalnih posledica. U zdravom organizmu postoji ravnoteža
prokoagulantnih i antikoagulantnih faktora hemostaze i pod normalnim okolnostima sistem funkcioniše u korist prevage antikoagulacije Hirurške procedure u tretmanu bolesti ginekološkh organa nose veliki rizik za
nastanak dubokih venskih tromboza , imajući u vidu anatomske odnose u maloj karlici i bogatu vaskularizaciju obturatornih i ilijačnih jama.Standarna terapijska doza heparina niske molekulske mase (LMWH) sa ciljem prevencije nastanka venskih tromboza, a u slučajevima blagog i umerenog rizika je 3.000-5.000U/24
h.U svim slučajevima visokog rizika, doza niskomolekulskog heparina se može udvostručiti . Veća sklonost
ka nastanku dubokih venskih tromboza u svakoj hirurškoj proceduri u maloj karlici naročito kod ženske populacije, stavlja primenu heparina niske molekulske mase kao primarni cilj u prevenciji eventualne tromboembolijske bolesti.

The case of concomitant occurrence of schwannoma of the ethmoid sinus and meningothelial hyperplasia in female patient without neurofibromatosis-2 is presented. The components of Schwannoma tissue and meningothelial hyperplasia cells islets were confirmed by histopathological and immunohistochemical examinations. Transitional zones of these two different tissues macroscopically as well as microscopically were not observed. Histological and immunohistochemical findings and possible pathogenesis of this uncommon tumor combination is discussed.

Cilj istraživanja je da se ispitaju neke karakteristike seksualnog ponašanja studenata (seksualna iskustva, upražnjavanje seksualnih odnosa, broj partnera, upotreba kondoma) i da se utvrde razlike u znanju, seksualnom ponašanju i percepciji rizika za oboljevanje od polnih bolesti. Studija preseka sprovedena je u populaciji studenata Visoke zdravstvene škole strukovnih studija u Beogradu. Ispitivani uzorak činilo je 246 studenata. Korišćen je anketni upitnik preuzet iz projekta „Zdravstveno stanje, zdravstvene potrebe i korišćenje zdravstvene zaštite stanovništva Srbije” iz 2000. godine koji je dizajniran od strane SZO. Upitnik je anonimno popunjavan. Za statističku obradu podataka korišćene su metode deskriptivne i eksplorativne analize, metode ukrštenih tabela uz primenu Pirsonovog χ2 testa. Analiza je urađena u softverskom paketu SPSS 13.0. Rezultati su prikazani tabelarno. Rezultati našeg istraživanja ukazuju da studenti odlično poznaju prenos HIV infekcije seksualnim putem, dok u nešto manjem procentu poznaju verikalnu transmisiju HIV infekcije. Dosledna upotreba kondoma nađena je kod polovine muških ispitanika i 2/5 ženskih ispitanika, dok po 1/5 ispitanika oba pola nikad ne koristi kondom. Nedosledna upotreba kondoma je glavni obrazac ponašanja u studentskoj populaciji. Ako pod bezbednim seksualnim odnosom podrazumevamo seksualni odnos uz upotrebu kondoma pri svakom seksualnom odnosu, sa jednom partnerom i ne upuštanje u seksualne odnose sa nepoznatim osobama, doći ćemo do zaključka da takav odnos upražnjava samo 1/3 naših studenata, a da se 2/3 rizično ponaša jer navode da nikad (17,8%), odnosno ponekad (43,5%) koriste kondom.

We investigated whether finasteride given before transurethral vapor resection (TUVRP) treatment has an impact on intra- and postoperative bleeding. Forty-two patients with diagnosis of benign prostatic hyperplasia (BPH) who had prostate volume (PV) > 30 mL underwent TUVRP: group A (n=21) received preoperatively finasteride 5 mg per day for median time of 7 months and group B (n=21) no finasteride. Preoperative evaluation include assessment of International Prostatic Symptom score (IPSS), Quality of Life (QoL), PV, maximum flow rate (Qmax) and postvoid residual (PVR). Patients mean age was 71.4± 2.1 vs 69.8 vs ± 3.4 years, respectively. Median PV was 55.5 ±21.2 vs 57.1 ±28.8 mL, respectively. Twenty-two (52%) patients had complete retention (29% vs 76%) (p<0.001). At baseline mean IPSS, QoL, Qmax and PVR were 18.1±5.9 vs 19.8±5.04, 3.3±1.7 vs 3.3±1.7, 8.1±4.4 vs 6.9±1.6 mL/s, and 146±106.9 vs 151.6±112.1 mL, respectively. The mean operation time was 59±16.8 vs 64±19.2 min, mean volume of irrigation fluid intraoperatively was 14.1±7.01 vs 15.2±8.1 L and postoperatively 7.0±2.1 vs 8.1 ±1.3 L, respectively. Mean blood loss was 312±85.9 vs 425±68.5 mL, respectively. The mean weight of resected tissue was 31.3±5.8 vs 30.75±8.4 gr, respectively. Mean duration of postoperative irrigation was 6.1 ± 4.7 vs 6.2 ±5.1 h, respectively. Thirty-six (85.7%) patients were discharged within 12 h postoperatively and the catheter is removed on 2.0±0.5 vs 2.5 ± 0.6 days, respectively. No patients received blood transfusion postoperatively. At 3 months postoperatively IPSS was 6.7±4.2 vs 5.2 ±2.01 (p<0.001), QoL 1.1±0.9 vs 1.1±0.7, Qmax 18.1±10.3 vs 17.5±8.1 mL/s (p<0.01) and PVR 41±46.1 vs 45±51.3 mL (p<0.05). The present study failed to demonstrate that preoperative treatment of BPH with finasteride did not have significant impact of perioperative bleeding at TUVRP.

Pravilan način ishrane je važan deo zdravog stila života i kao takav treba da bude usvojen u najmlađem životnom dobu. Cilj rada je bio da se utvrde navike u ishrani studenatske populacije. Istraživanje je dizajnirano kao studija preseka u kome je učestvovalo 246 studenata Visoke zdravstvene škole strukovnih studija u Beogradu. Korišćen je anketni upitnik iz istraživanja „Zdravstveno stanje, zdravstvene potrebe i korišćenje zdravstvene zaštite stanovništva Srbije” iz 2000. godine, dizajniran od strane SZO. Za statističku obradu podataka korišćene su metode deskriptivne i eksplorativne analize, metode ukrštenih tabela uz primenu Pirsonovog χ2 testa. Analiza je urađena u softverskom paketu SPSS 13.0. Rezultati istraživanja pokazuju da svakodnevno doručkuje nešto više od polovine studenata, ruča 81,7%, a večera polovina studenata. Mleko i mlečne napitke svakodnevno konzumira po jednu šolju 2/5 ispitanika, dok je sir korišćen 1-2 puta nedeljno. Krompir kao i sve vrste mesa, riba i jaja u ishrani koriste se jednom do dva puta nedeljno. Sveže povrće svakodnevno je uzimala samo trećina studenata, a sveže voće nešto više od trećine. Oko 1/5 ispitanika svakodnevno uzima slatko pecivo i slatkiše. Samo 1/5 koristi crni ražani hleb. Kao najčešći namaz u ishrani studenti koriste margarin, majonez, maslac i kajmak. Od ukupnog broja ispitanika nikada ne razmišlja o svom zdravlju pri izboru načina ishrane 7,3% studenata, ponekad razmišlja 43,5%, često 39,8%, dok 9,3% ispitanika uvek razmišlja o svom zdravlju pri izboru načina ishrane.

Although the first balloon dilation of aortic stenotičnog valve in the fetus was performed successfully as early as 1989th , the fetal cardiac intervention procedures are still in experimental medicine and performed in a few centers in the world. Interventional cardiology procedures at this time in the application of the fetuses with aortic stenosis, fetuses with stenosis / atresia of the pulmonary artery and hypoplasia of fetuses with left ventricle and restrictive međupretkomorskim hole.

Lekar koji učestvuje u prenatalnom skriningu i dijagnostici kongenitalne srčane bolesti mora biti familijaran sa potencijalnim uticajem tehničkih faktora u postizanju najboljih diagnostičkih prikaza srca i njegovih struktura, a sve u okviru prihvatljivih termalnih i mehaničkih sigurnosnih limita ultrazvučnih procedura u obstetriciji. Znanje adekvatne optimizacije gain-a, uvećanja ultrazvučne slike, korišćenje compound imaging-a i harmonic imaging-a su preduslovi kvalitetnog pregleda. Ostali važni faktori koji utiču na pregled i koji treba da se uzmu u obzir su gestaciona starost u momentu pregleda, maternalni telesni habitus, fetalni pokreti i pozicija i primenjena frekvenca ultrazvučnog talasa. Nekad je neophodno da se sačeka optimalni fetalni položajda bi prikazali željene strukture, a da bi se to postiglo nekad se pacijent mora ponovo pregledati nekom drugom prilikom.

Lymph node metastasis in patients with colorectal carcinoma is bed prognostic factor. High level of CEA and CA 19-9 tumor markers before surgery have had a high sensitivity and also is a combination of high specification, especially in late stage cases. Considering that, general attention was to proof a correlation between level of CEA and CA 19-9 tumor markers before surgery and number of nodal metastasis in these patients. Our study included 102 patients with colorectal carcinoma. We measured level of CEA and ca 19-9 tumor markers before surgery and compared it with number of dissected lymph node metastasis after surgery as same as comparing with Duke’s stage of carcinoma. Average level of CEA tumor marker before surgery was 44,59 μg/mol. Lowest rate was 0,8 μg/mol ant the higher was 551 μg/mol. Average level of CA 19-9 before surgery was 258, 8696 U/mol. Average number of dissected lymph nodes per patient was 14,62 within average 2,5895 was nodal metastasis. There is a high statistically signification between CEA and CA 19-9 tumor markers level before surgery and level of Duke’s classification stage after surgery. Number of nodal metastasis is correlated with level of CEA before surgery. Level of CA 19-9 before surgery is not statistically significant for number of nodal metastasis. During this examination we noticed a high increasing of CEA and CA 19-9 tumor marker levels before surgery in patients with C2 Duke’s stage with more than 4 lymph nodal metastasis found after surgery. In this patients level of CEA was higher 45,78 μg/ml comparing with patients in C1 Duke’s stage who have had CEA level 6,07 μg/ml. In patients with C2 Duke’s stage average value of CA 19-9 was extremely high – 71 U/ml. High level of CEA and CA19-9 is statistically significant for staging of colorectal malign disease as same as for number of nodal metastasis.

Funkcionalna definicija matične ćelije podrazumeva da je to najmladja ćelija ljudskog organizma koja poseduje izvanredan kapacitet samoobnavljanja i sposobnost diferenciranja u specijalizovane tipove ćelija. Osnovna podela je na embrionalne matične ćelije i adultne matične ćelije. Embrionalne matične ćelije predstavljaju najmladje ćelije ljudskog organizma. One su pluripotentne i imaju sposobnost da se pretvore u otprilike 220 vrsta ektoderma, mezoderma i endoderma. Adultne matične ćelije su nediferentovane ćelije koje se pojavljuju u odraslom tkivu.. I one imaju sposobnost da se samoobnavljaju i proizvode diferentovane potomke, ali su one multipotentne i kapacitet diferentovanja im je ograničen. Njihova osnovna funkcija je obnavljanje oštećenog tkiva. Obzirom da kardiovaskularna oboljenja predstavljaju jedan od najčešćih uzroka morbiditeta i mortaliteta čitavog čovečanstva, interesovanje za korišćenje matičnih ćelija kod kardioloških oboljenja je u žiži interesovanja naučnika.