Trisomy 13 (Sy Patau) is a clinically severe entity. 85% of the patients do not survive beyond one year, and most children die before completing six months of age. We report a female child, 30 day old, white, the third child of a non-consanguineous couple, who presented trisomy 13. The child was born at term, from a vaginal delivery, weighing 3200 g. The second day of life the development of respiratory distress translated ino KBC Kragujevac (release list no.29623). The initial clinical examination detected shisis primariy and secunday palate, ASD, stenosis rami AP, polidactily pedis dextri, microcornea and microftalmia. After 27 days of hospitalization in KBC Kragujevac, transferred to the Institute for mother and child New Belgrade, where he died after three days of receipt. During hospitalization blood samples were taken for determination of kariotip. Parents are advised that in case of subsequent pregnancies occur in the genetic counseling of the Institute for prenatal diagnosis.

The development of Zemun Hospital in the 19th century was followed by better work conditions and an increasing number of patients. The arrival of doctor Vojislav Subotić to the hospital and his work were key moments in the general improvement of the hospital. Since 1887, the hospital was administered by a society known as „Sisters of Charity of Saint Vincent De Paul“. By the end of 1891, they had constructed a new hospital building.

The 20th century was the most eventful period in the history of Zemun Hospital and it brought many changes. Working through out both world wars, the hospital staff aided those who were wounded or ill, both soldiers and civilians. Throughout this period, the hospital worked in three different countries, under various administrations and owners.

Zemun hospital, the present-day Clinical Hospital Zemun-Belgrade, was founded in 1784, is the oldest hospital in the Serbia. For over two centuries, it blazed the trial and still pioneers in the application of numerous advanced medical achievements and knowledge in this region.

Osteopoikilija je jedna manje poznata anomalija koštanog razvoja koja se pojavljuje familijarno. Kao posebnu pojavu prvi je opisao 1915 god. Albers Schonberg a u isto vreme nezavisno od njega opisuje osteopoikiliju Ledoux Lebard. Voorhoeve 1924 god. Opisuje ovo stanje kao Osteopathia striata (Voorhoev –a bolest).

Osteopoikilija pripada grupi nesavršenih osteogeneza koja se karakterišu u nedovoljnoj diferencijaciji spongiozne kosti zbog čega se u odgovarajućim delovima skeleta pojavljuju mnogobrojna ognjišta osteoskleroze. Oboljenje je nasledno i postoje brojni opisi familijarnog pojavljivanja u nekoliko pokoljenja jedne porodice. U ovom radu prikazujemo jedan slučaj osteopoikilije koji je otkriven kod muškarca starosti 25 godina, koji se javio ambulantno u Traumatološku službu KBC Zemun.

Persistent infection of Human papillomavirus (HPV) is the strongest epidemiological factor associated with intraepithelial neoplasia and cervical cancer. These days, infection with Human papillomavirus is the most common type of sexually transmitted disease. In most cases, infection is asymptomatic and it remains undiagnosed. Women infected with high-risk types of the virus are at greater risk of developing severe dysplastic changes or cancer. The aim of this study was to examine the association between HPV type 16/18, cytology, colposcopy, biopsy and risk factors of developing intraepithelial lesions of low L-SIL and a high level of H-SIL. The study included 864 patients who had undergone detection of HPV type 16/18 DNA using in situ hybridization. All study participants were divided into three categories according to the presence of H-SIL, L-SIL and benign histologic findings. In the case study group that had L-SIL and H-SIL there was a significant higher percentage of HPV infection than in the group of patients with benign histologic findings. The percentage of H-SIL is highest in patients who had HR-HPV infection with types 16/18, sexual intercourse before 16 the age and two to five sexual partners. This study indicates that among the H-SIL intraepithelial neoplasia, there is a high presence of HR-HPV 16/18 related to the number of sexual partners and early sexual intercourse at a younger age as a statistically significant presence of these genotypes with L-SIL intraepithelial neoplasia.

Gestational diabetes mellitus and maternal overweight and obesity are associated with increased risk for adverse maternal and perinatal outcomes, such as fetal overgrowth. Although most studies addressing the effects of maternal BMI on adverse outcomes include women with GDM, a little is known about associations between maternal BMI and fetal metabolic status evaluated by ultrasonography means. One of the ultrasound parameter of glycemic controlis the measurement of fetal liver length. Prospective study of 385 women with monofetal pregnancies and established risk for GDM underwent mid-trimester ultrasound exam, during which fetal liver length were measured. After exam, body mass index (BMI) was determined for each patient. Each participant underwent 100 g fasting oral glucose challenge test (oGTT) in order to confirm or to exclude diagnosis of GDM. There was a statistically highly significant positive correlation between the BMI and fetal liver length for the entire sample (N=385; p<0.001; R=+0.55) as well in the sample of GDM patients (N=96; p<0.001; R=+0.58) and controls (N=289; p<0.001; R=+0.33). Maternal BMI has impact on fetal liver length assessed by ultrasound exam. This influence is even higher in GDM.