Trisomy 13 (Sy Patau) is a clinically severe entity. 85% of the patients do not survive beyond one year, and most children die before completing six months of age. We report a female child, 30 day old, white, the third child of a non-consanguineous couple, who presented trisomy 13. The child was born at term, from a vaginal delivery, weighing 3200 g. The second day of life the development of respiratory distress translated ino KBC Kragujevac (release list no.29623). The initial clinical examination detected shisis primariy and secunday palate, ASD, stenosis rami AP, polidactily pedis dextri, microcornea and microftalmia. After 27 days of hospitalization in KBC Kragujevac, transferred to the Institute for mother and child New Belgrade, where he died after three days of receipt. During hospitalization blood samples were taken for determination of kariotip. Parents are advised that in case of subsequent pregnancies occur in the genetic counseling of the Institute for prenatal diagnosis.

The development of Zemun Hospital in the 19th century was followed by better work conditions and an increasing number of patients. The arrival of doctor Vojislav Subotić to the hospital and his work were key moments in the general improvement of the hospital. Since 1887, the hospital was administered by a society known as „Sisters of Charity of Saint Vincent De Paul“. By the end of 1891, they had constructed a new hospital building.

Cysts of the spleen are rare disease that affects the spleen. They are divided into primary and secondary in relation to the etiology and histopathology. We report two young patients of a boy aged 16 and a girl of 15 godina. Ultrasonography and CT of the abdomen showed a large cystic mass in the spleen unclear origin. On laparotomy for both the patient was found a large cyst that reached to the upper pole of the spleen and required total splenectomy. Histopathology showed fibrous cyst wall with areas of hyaline degeneration below which there is significant blood kongstion.Etipatogenesis and different modalities of treatment for cysts of the spleen are questionable. Although pseudocysts of the spleen are rare, they must be considered in the differential diagnosis of abdominal masses in the upper abdomen in young adolescents.

The 20th century was the most eventful period in the history of Zemun Hospital and it brought many changes. Working through out both world wars, the hospital staff aided those who were wounded or ill, both soldiers and civilians. Throughout this period, the hospital worked in three different countries, under various administrations and owners.

Zemun hospital, the present-day Clinical Hospital Zemun-Belgrade, was founded in 1784, is the oldest hospital in the Serbia. For over two centuries, it blazed the trial and still pioneers in the application of numerous advanced medical achievements and knowledge in this region.

Rak dojke je najčešći maligni tumor i jedan od vodećih uzroka prevremene smrti žena u Republici Srbiji. Stope razboljevanja i umiranje od raka dojke su neprestano raste u poslednjih nekoliko decenija. U više od polovine slučajeva, rak dojke je otkrivena u poodmakloj fazi. U Republici Srbiji, neinvazivni rak dojke se nalazi samo u 1% slučajeva, a procenat bolesti lokalizovane samo u grudima je 37%. Uzimajući u obzir ove podatke, potrebno je upotrebiti sve dostupne metode snimanja i relevantne medicinske specijalnosti, a sve u cilju postavljanja dijagnoze raka dojke u ranoj fazi, jer je to jedini mogući način da se potpuno izleči ova teška bolest.

Persistent infection of Human papillomavirus (HPV) is the strongest epidemiological factor associated with intraepithelial neoplasia and cervical cancer. These days, infection with Human papillomavirus is the most common type of sexually transmitted disease. In most cases, infection is asymptomatic and it remains undiagnosed. Women infected with high-risk types of the virus are at greater risk of developing severe dysplastic changes or cancer. The aim of this study was to examine the association between HPV type 16/18, cytology, colposcopy, biopsy and risk factors of developing intraepithelial lesions of low L-SIL and a high level of H-SIL. The study included 864 patients who had undergone detection of HPV type 16/18 DNA using in situ hybridization. All study participants were divided into three categories according to the presence of H-SIL, L-SIL and benign histologic findings. In the case study group that had L-SIL and H-SIL there was a significant higher percentage of HPV infection than in the group of patients with benign histologic findings. The percentage of H-SIL is highest in patients who had HR-HPV infection with types 16/18, sexual intercourse before 16 the age and two to five sexual partners. This study indicates that among the H-SIL intraepithelial neoplasia, there is a high presence of HR-HPV 16/18 related to the number of sexual partners and early sexual intercourse at a younger age as a statistically significant presence of these genotypes with L-SIL intraepithelial neoplasia.

Study objective was to test the relationship between maternal body mass index (BMI) and fetal abdominal subcutaneous fat tissue (ASCT) measured by ultrasound. The total number of pregnant women enrolled in the prospective study was 280. For all participants BMI was determined. Study participants underwent ultrasound exam at 32nd week of gestation and ASCT was measured. Positive correlation has been found between ASCT and maternal BMI (p<0.01, r=0.1612). The study showed that intrauterine growth and development is partially regulated by the maternal BMI.