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Volume 39, Issue 1, 2025

Online ISSN: 3042-3511

ISSN: 3042-3503

Volume 39 , Issue 1, (2025)

Published: 31.03.2025.

Open Access

Welcome to Issue 39, No. 1 – the first of our two annual publications for this year. Inside, you'll find a curated selection of articles. Start your year with the essential knowledge and perspectives offered in this timely edition

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01.12.2013.

Review Article

Distribution of dermatological diseases in children examined in the Office of Dermatology KBC Zemuna three-year retrospective study

The three year study has objective to demonstrate the number of pediatric patients up to 15 years of age examined and treated in Department of dermatovenereology, and the distribution of the most common skin diseases of the childhood. During 2011.2012. and 2013. there has been 10210 pediatric patients examined , with their parents or guardians giving anamnestic data. Than skin, hair and nails has been inspected with bacteriological or mycological swabs examination. The total count of patients in three years has been 85371, out of it 10210 pediatric patients examined by dermatovenereologist (11,96%). The most common diseases found were verrucae vulgares (53%), dermatitis atopica (15%), acne (8%), mollusca contagiosa (8%), dermatitis allergica (7%), scabies (4%). Distribution of dermatopediatric diseases in our region corresponds to findings in europian countries, except higher count of scabies patients. Pediatric dermatology is very sensitive field of dermatology, that requires multidisciplinary tretament with pediatricians, allergologists, pulmologists, otorhynolaryngologists, psychologists.

Svetlana Grubor, Branka Brankovic-Zirojevic, Divna Gajic-Macanovic, Dragica Markovic

01.12.2013.

Review Article

Odeljenje internisticke intenzivne nege - prve dve godine rada

Zoran Gluvic, B. Mitrovic, Biljana Lazovic-Popovic, N. Jevic, M. Radovic, Aleksandar Neskovic

01.12.2013.

Review Article

Clinical Hospital Center Zemun through the centuries -18 th century

Zemun hospital, the present-day Clinical Hospital Zemun-Belgrade, was founded in 1784, is the oldest hospital in the Serbia. For over two centuries, it blazed the trial and still pioneers in the application of numerous advanced medical achievements and knowledge in this region.

Sanja Milenkovic, Jasmina Milanovic

01.12.2013.

Review Article

Snimanje dojki: multidisciplinarni pristup -prikaz slučaja

Rak dojke je najčešći maligni tumor i jedan od vodećih uzroka prevremene smrti žena u Republici Srbiji. Stope razboljevanja i umiranje od raka dojke su neprestano raste u poslednjih nekoliko decenija. U više od polovine slučajeva, rak dojke je otkrivena u poodmakloj fazi. U Republici Srbiji, neinvazivni rak dojke se nalazi samo u 1% slučajeva, a procenat bolesti lokalizovane samo u grudima je 37%. Uzimajući u obzir ove podatke, potrebno je upotrebiti sve dostupne metode snimanja i relevantne medicinske specijalnosti, a sve u cilju postavljanja dijagnoze raka dojke u ranoj fazi, jer je to jedini mogući način da se potpuno izleči ova teška bolest.

Dejan Jovanovic, Biserka Vukomanovic-Djurdjevic, Leposava Sekulovic, Zoran Milutinovic

01.12.2013.

Review Article

Od diferencijalno dijagnostičke analize i terapijskog pristupa cervikalne mijelopatije do uspešnog hirurškog lečenja

Cilj ovog prikaza slučaja je da na osnovu analizirane kliničke slike i raspoloživog ciklusa lečenja istakne značaj patološkog entiteta sekundarne cervikalne mijelopatije kao posledica degenerativnih spondilotičnih promena na cervikalnim pršljenovima. Ujedno, cilj je bio da se istakne značaj hirurškog tretmana, kao metoda prvog izbora u procesu uspešnog lečenja. Mi smo analizirali sveobuhvatne podatke iz medicinske dokumentacije, rezultate neuroloških kliničkih i dijagnostičkih ispitivanja:, evocirane potencijale, rezultate lumbalne punkcije, imuno - serološke nalaze i rezultate magnetne rezonance. Pretstavljen je pacijent sa naglo nastalom i progresivno razvijenom kliničkom slikom kvadripareze, prvenstveno na donjim ekstremitetima. Sprovedenim kliničko dijagnostičkim ispitivanjem dobijeni su rezultati koji su ukazali na sekundarno nastalu cervikalnu mijelopatiju, na terenu degenerativnog procesa na cervikalnom regionu. Operativno lečenje je bio izbor i metoda lečenja koja se pokazala kao dobar izbor sa uspešnim ishodom. Krajnji ishod lečenja je bio upotpunjen adekvatnom fizikalnom rehabilitacijom. Ova prikaz slučaja predstavlja ilustraciju povoljnog ishoda hirurškog lečenja cervikalne mijelopatije na terenu degenerativnih spondilotičnih promena cervikalne kičme. To je metoda prvog izbora u poboljšavaju funkcionalnog statusa pacijenata i ujedno način da se zaustavi napredovanje patološkog procesa i neurološkog deficita pacijenata.

Dragoslava Jovanovic

01.12.2013.

Review Article

Korelacija između metaboličkog sindroma i simptoma donjih partija urotrakta

Sredovečni muškarac često ima simptome donjih partija urotrakta (SDPU) kao posledice benignog uvećanja prostate (BUP). Korelacija između metaboličkog sindroma (MS) i SDPU ostaje predmet debate. Ova studija ima za cilj da ispita uticaj MS na SDPU kod sredovečnih muškaraca imali opšti lekarski pregled. Svi pacijenti su podeljeni u 2 grupe u zavisnosti od prisustva 3 ili više faktora rizika uključujući povišen krvni pritisak, obim struka, glikemiju,HDL holesterol i trigliceride. Volumen prostate (VP), određen pomoću transrektalnog ultrazvuka, i nivo prostata specifičnog antigena (PSA) su upotrebljeni za podgrupnu analizu, uključujući odredjivanje ukupnog Internacionalnog Prostata Simptom Skora (IPSS), sa iritativnim i opstruktivnim skorom, kao i ocenu kvaliteta života. Tri stotine pedeset četiri muškarca, srednje starosti 55.6 ± 9.71 godina, su uključeni u studiju. U zavisnosti od navedenih kriterijuma za MS, 108 (30.5%) je imalo MS i predstavljalo je studijsku grupu, dok je 246 (69.5%) MS-negativnih muškaraca formiralo kontrolnu grupu. Antropometrijski indeksi, metabolički parametri i učestalost arterijskie hipertenzije su bili veći kod grupe sa MS u odnosu na grupu bez MS (p<0.0001). Grupa sa MS (7.89 ± 6.63 prema 6.85 ± 6.52) je imala manju srednju vrednost ukupnog IPSS, manju slabost mlaza urina pri mokrenju (1.24 ± 1.60 prema 0.95 ± 1.50, p= 0.021) i manji stepen IPSS gradiranja (p=0.014). Kod većeg VP (> 30 mL), ukupni IPSS, iritativni i opstruktivni skor, urgentni pozivi na mokrenje i nepotpuno pražnjenje bešike su bili manje izraženi kod grupe sa MS (p<0.05). U grupi sa višim prostata specifičnim antigenom (PSA) (> 0.93 ng/ mL), muškarac sa MS je imao značajno niži IPSS, opstruktivni skor, nepotpuno pražnjenje mokraćne bešike i slab mlaz. Negativna povezanost izmedju iritativnih i opstruktivnih smetnji, intenzitet SDPU i MS postaje naročito izražena sa povećanjem broja faktora rizika MS (p<0.0001). Odnos šanse (OŠ) za umeren i izražen SDPU je bio signifikantno manji kod muškaraca sa 3 (OŠ 0.61; 95% interval poverenja (IP) 0.40-0.94) ili 5 (OŠ 0.32; 95% IP 0.11-0.95) faktora rizika. Muškarci u grupi sa MS imaju manju verovatnoću da imaju umeren do žestok skor SDPU (OŠ 0.58; 95% IP 0.41-0.83). Studija je pokazala da MS ima povoljan efekt na SDPU, uključujući iritativne i opstruktivne simptome kod zdravih sredovečnih muškaraca. Beneficirajući efekat je bio najizraženiji kod muškaraca sa uvećanom prostatom i/ili višim vrednostima PSA.

Djordje Argirovic, Aleksandar Argirovic

01.12.2013.

Review Article

ORIGINALNI RADOVI CASE REPORTS Mouth opening scope in the patients with systemic sclerosis -Simultaneously application of a hyperbaric oxygenation and physical therapy

During our perennial work with patients with systemic sclerosis we noticed that after the therapy of hyperbaric oxygenation (HBOt) they were able to their mouths open more easily. This treatment effect became visible when we started treating our patients with physical therapy. In order to find out whether this was patients’ subjective impression or an objective increase, we decided to keep the track of changes in mouth circumference before and after combined therapy of hyperbaric oxygenation and physical therapy. We treated the patients with ten HBO treatments at 2.0 ATA. Physical therapy lasted for ten days. First, the patients went to phototherapy with infrared rays (Solux lamp) for 15 minutes, at 40 cm intervals, perpendicularly, and then they went to kinesitherapy for mimic musculature in front of a mirror. Measurements before and after the therapy have shown a statistically significant difference and proved that the combination of HBO therapy and physical therapy has its place in treating these patients.

Davorka Milacic, Koviljka Cobeljic, Radmilo Isakovic

01.12.2012.

Review Article

Malignant giant cell type fibrohistiocitom of the abdominal wall

Malignant fibrous histiocytoma is a condition involving a tumor of the bone or soft tissues. The tumor often appears in the legs or arms, but it can develop in other parts of the body. The disease is the most common soft tissue cancer that is diagnosed in older adults, and is often diagnosed in people between the ages of 50 and 70. We present a case of giant cell malignant fibrohistiocytoma of the abdominal wall. A 77 year old woman was admitted for further evaluation and treatment of tumor in the right ingvinal region of the abdominal wall. She claimed that tumor have appeared 3 mounths earlier and it was characterized by rapid growth and tenderness. NMR demonstrated expansive heterogeneous mass, 18,6x16,2cm of diameter. We performed total extirpation of the tumor. Postoperative period was uncomplicated and she was discharged from the hospitaly in good condition. Pathohystological examination confirmed malignant fibrous histiocytoma. Depending on the stage of disease and the depth of invasion by the tumor, surgical resection is the treatment of choice. Radiotherapy, chemotherapy, and immunotherapy are other therapeutic modalities. Long term followup with regular chest X-rays and CT scans of the abdomen to detect tumor recurrence, metastasis and any lymph node involvement are mandatory.

Nebojsa Mitrovic, Aleksandar Mitrovic

01.12.2012.

Review Article

Helicobacter pylori infection and comorbidity: Our diagnostic and therapeutic modalities

The discovery of Helicobacter pylori (Hp) bacteria and causal relationship of Helicobacter pylori infection with the origin of chronic gastritis, stomach and duodenal ulcer and stomach cancer represents an epochal event of the new age. The goal of the study is to examine the incidence of Helicobacter pylori infection of stomach and prove the connection between Helicobacter pylori infection and stomach and duodenum diseases (non-ulcer gastropathy, stomach ulcer, and duodenal bulb ulcer and stomach cancer). The study encompassed 250 randomly selected examinees of both genders and different age categories. All the examinees were subjected to quick urease test (QUT) from antral bioptate and stomach corpus acquired by upper gastrointestinal endoscopy with standard forceps. Hp positive examinees were subjected to one of four therapy protocols for eradication of Hp. The acquired data were treated with application of descriptive statistical methods (SV, SD, Min, MAX) and analytical statistical methods (Student t test, Hi quadrat test, Kruskal-Walish test, Mann-Whitny U-test, Wilcoxon test, ANOVA variant analysis, Spearman and Pearson correlation). 250 examinees tested by quick urease test (QUT), 54% were positive and 46% were negative (p>0.05). The proportion by genders between QUT positives and QUT negatives was approximately the same (p>0.05). Non-ulcer gastropathy was a dominant finding with both QUT negatives (92.2%) and QUT positives (77%) (p<0.01). The highest rate of eradication of Helicobacter pylori infection was shown by protocols B and D (75%), then protocol A (71%) and protocol C (57.2%) (p>0.05). Quick urease test (QUT) which requires upper digestive endoscopy and biopsy of stomach epithelia samples represents a minimum of invasive diagnostics of Helicobacter pylori infection and a minimum of confirmation of eradication in our conditions. Therapeutic protocols B and D have shown the highest rate of success in eradication with our patients.

Sabir Sagdati, Srbislava Milinic, Predrag Dugalic

01.12.2012.

Review Article

The duration of the postoperative period in patients with associated fractures of the lower leg and ankle

Fractures in the level of the ankle are among the most common fractures. A separate entity is associated fractures at the level of the ankle joint with fractures of the lower leg. The aim is to determine what the impact of certain preoperative factors [length preoperative period, the complications of surgical treatment and antibiotics] the length of postoperative hospital stays. This retrospective study included patients were treated surgically with associated fracture of the lower leg and ankle in the Department of Orthopedics and grammatology KBC Zemun between 2003rd by 2011. and were divided into three groups according to the duration of preoperative hospital stay. The length of postoperative hospital stay significantly affect the time to completion of the operation (ρ = 0.405, p <0.01) for the occurrence of complications (ρ = 0.465, p <0.01) and duration of antibiotic use (ρ = 0.580, p <0, 01). The average length of hospital stay in patients with complications was 19 registered (Med 18) days, whereas in patients without complications 10 registered (Med 9) days. There was a statistically significant difference in the length of hospital recovery compared to various complications (log rank = 35.74, DF = 5, p <0, 01). It is these fractures that previously disposed of as such a treatment leads to less frequent complications, a shorter stay in hospital patients and therefore lower costs of the treatment.

Branislav Vracevic, Dejan Ristic, Nebojsa Jovanovic, Aleksandar Stankovic, Biljana Stankovic, Voja Cvetkovic, Aleksandar Vojvodic, Zoran Rosic, Edin Redzepagic, Marko Zunic

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