Osteopoikilija je jedna manje poznata anomalija koštanog razvoja koja se pojavljuje familijarno. Kao posebnu pojavu prvi je opisao 1915 god. Albers Schonberg a u isto vreme nezavisno od njega opisuje osteopoikiliju Ledoux Lebard. Voorhoeve 1924 god. Opisuje ovo stanje kao Osteopathia striata (Voorhoev –a bolest).

Osteopoikilija pripada grupi nesavršenih osteogeneza koja se karakterišu u nedovoljnoj diferencijaciji spongiozne kosti zbog čega se u odgovarajućim delovima skeleta pojavljuju mnogobrojna ognjišta osteoskleroze. Oboljenje je nasledno i postoje brojni opisi familijarnog pojavljivanja u nekoliko pokoljenja jedne porodice. U ovom radu prikazujemo jedan slučaj osteopoikilije koji je otkriven kod muškarca starosti 25 godina, koji se javio ambulantno u Traumatološku službu KBC Zemun.

Magnetic resonance imaging (MRI, magnetic resonance tomography - MRT, nuclear magnetic resonance - NMR, English: Magnetic Resonance Imaging - MRI) is a modern non-ionizing, noninvasive radiological methods of examination which visualize and diagnose anatomical, morphological and functional state of the organs of the human body. MRI is the only one of the important radiological information system. The work of MR is based on the application of a strong homogeneous magnetic field and modern computer technology. This paper presents the basic MRI, history of MRI, magnetic field strength in MR, MR physical principles, principles of MR and MR sequences. Conclusion: MRI is a sovereign, dominant and non-ionizing radiological examination method, which are enriched radiological imaging techniques of pathological states authority, and whose work requires appropriate knowledge of physics, medicine and computer science.

Postoji relativno malo podataka u literaturi koji imaju za cilj procenu korelacije između kvaliteta ishrane i simptoma donjih partija urotrakta (SDPU). Cilj ove studije je da proceni povezanost izmedju kvaliteta ishrane i SDPU. Naša hipoteza je bila da je izbalansirana zdrava ishrana udružena sa manjom učestalošću SDPU. Studija obuhvata 852 pacijenata starosti >40 godina od kojih je 724 (85%) kompletiralo urinarni upitnik. Primenjena je bivarijantna analiza da se ispita stepen SDPU kod pacijenata sa dobrom i lošom ishranom. Multivarijantna regresiona analiza je primenjena da se proceni uticaj demografskih faktora kod pacijenata sa ili bez SDPU u zavisnosti odgodina starosti, pušenja, dijabetesa, konzumiranja alkohola, gojaznosti i fizičke aktivnosti. Pošto smo isključili iz analize 31 pacijenta sa karcinomom prostate, naša studija je obuhvatala 693 muškaraca od kojih je 139 (20%) imalo najmanje jedan simptom indikativan za SDPU (63 iritativne, 46 opstruktivne i 30 oba simptoma). Veća verovatnoća za pojavu SDPU je postojala kod seoske populacije (p<0.0001), nepušača (p<0.0001), dijabetičara (P<0.0001), starijih muškaraca (p<0.0001), sa višim PSA (p<0.0001) i dijagnozom uvećanja prostate (p<0.0001). Umerena i intenzivna fizička aktivnost i unos alkohola su bili češće zastupljeni kod muškaraca bez SDPU (p<0.0001). Nadjena je veća učestalost SDPU kod muškaraca sa malim unosom mlečnih proizvoda (22.4%:16.4%) (p=0.0013), oskudnim unosom proteina (24.6%:17.9%)(p=0.012), generalno lošom ishranom (28.2%:17.8%) (p=0.012) i malom raznolikošću ishrane (26.1%:17.6%) (p=0.001). Multivarijantna analiza je pokazala da nezdrava ishrana, seoska populacija i stariji muškarciimaju veći rizik za pojavu SDPU, dok je unos alkohola imao protektivno dejstvo na SDPU.

Cysts of the spleen are rare disease that affects the spleen. They are divided into primary and secondary in relation to the etiology and histopathology. We report two young patients of a boy aged 16 and a girl of 15 godina. Ultrasonography and CT of the abdomen showed a large cystic mass in the spleen unclear origin. On laparotomy for both the patient was found a large cyst that reached to the upper pole of the spleen and required total splenectomy. Histopathology showed fibrous cyst wall with areas of hyaline degeneration below which there is significant blood kongstion.Etipatogenesis and different modalities of treatment for cysts of the spleen are questionable. Although pseudocysts of the spleen are rare, they must be considered in the differential diagnosis of abdominal masses in the upper abdomen in young adolescents.

The development of Zemun Hospital in the 19th century was followed by better work conditions and an increasing number of patients. The arrival of doctor Vojislav Subotić to the hospital and his work were key moments in the general improvement of the hospital. Since 1887, the hospital was administered by a society known as „Sisters of Charity of Saint Vincent De Paul“. By the end of 1891, they had constructed a new hospital building.

The 20th century was the most eventful period in the history of Zemun Hospital and it brought many changes. Working through out both world wars, the hospital staff aided those who were wounded or ill, both soldiers and civilians. Throughout this period, the hospital worked in three different countries, under various administrations and owners.

An increasing number of studies support the concept that cancer stem cells (CSCs) are responsible for initiation, growth and metastasis of malignant neoplasms. CSCs represent the population with tumor initiating potential, and possess the properties of normal stem cells, including the ability of self-renewal and perpetual proliferation, as well as the specific potential of multilineage differentiation, which underlies tumor heterogeneity. The persistence of CSCs has been considered the main culprit for tumor relapse and metastasis, since conventional oncologic protocols do not eradicate CSCs. Development of specific therapeutic strategies targeting CSCs may contribute to significant advance in cancer treatment. The crucial step in CSC targeted therapy development, as well as in subsequent efficacy validation, is the identification of specific stem cell markers, where the role of pathologist is of major significance.

The same legal regulations applied for medical doctors involved in patients treatment, also refer to doctors that do not manage therapy, but whose professional activity is essential for providing adequate diagnostics. this group of professionals include pathologists, which is proven by the actual forensic practice. In modern medicine, the role of pathologists is of extreme importance in the diagnostics of many diseases. In this paper, based on presentation of particular cases from the forensic practice and literature data, the possible forms of mistakes in the work of pathologists and their associates are shown, as well as the causes and the consequences of such mistakes, together with the characteristics of the legal procedures and the significance of adequate medicolegal expertise in these cases.

The inflammatory myopathies are heterogeneous aquired diseases which are grouped together because of their imflammatory nature. In this group are included polymyositis, adult and juvenile dermatomyositis and inclusion body myositis. The aim of this review is to point out the basic principles od differential diagnosis of idiopathis aquired inflammatory myopathies. the general pathologists in the rutine practice are very often confronted with skin or muscle samples for many reasons, and so they have to be informed with these basic entities.