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Volume 39, Issue 1, 2025

Online ISSN: 3042-3511

ISSN: 3042-3503

Volume 39 , Issue 1, (2025)

Published: 31.03.2025.

Open Access

Welcome to Issue 39, No. 1 – the first of our two annual publications for this year. Inside, you'll find a curated selection of articles. Start your year with the essential knowledge and perspectives offered in this timely edition

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01.12.2015.

Review Article

Epidemiological and clinical picture of scabies in municipality of Podgorica in a Ten-year Period (2006-2015)

The objective of this study is to obtain data on the incidence of scabies in the city of Podgorica, the observed ten-year period (2006 to 2015) and its incidence in relation to age and gender. The second objective was to find out whether the incidence is declining to the observed period.Scabies is contagious, worldwide disease, sporadically or in epidemic form. For the creation of this parasitosis, importance is given to the socioeconomic status, living conditions, sexual promiscuity, the development of resistant populations of the parasite. In developed countries, the incidence shows a cyclical fluctuation, with long, calm intervals, while in developing countries the incidence is constantly high. The disease is spread by close physical contact, often spreading within families and it is subject to mandatory reporting. In this paper, we used the official data of the Institute for Public Health in Podgorica, which included all clinical cases reported for the ten years, a total of 1,141 people, which are classified according to age and sex, for each year. Scabies as parasitism has been reported in the highest percentage among the younger population, aged 0-20 years, more common among males. The largest number of patients is registered in 2012.

Marijan Bakic, Mirjana Bakic, Marija Bakic, Masa Golubovic

01.12.2015.

Review Article

Colorectal cancer screening methods

Colorectal cancer (CRC) is an important social and medical problem. Complete recovery can be achieved only if the disease is diagnosed in the early stages, most common by screening methods. Studies have shown that screening methods reduce the incidence and mortality of colorectal cancer. The methods for colorectal screening can be divided into tests that allow the detection of cancer (fecal occult blood test and fecal DNA test) and morphological tests that allow diagnosis of cancer or adenomatous polyps (flexible sigmoidoscopy, colonoscopy, double contrast barium enema, CT colography ). In people with average risk of disease, screening begins at 50 years and performed on one of the following: fecal occult blood test (every year), flexible sigmoidoscopy (every 5 years), colonoscopy (every 10 years), double contrast barium enema (every 5 years) or CT colography (every 5 years). Colonoscopy is the preferred method, and is used as a confirmatory method, if the any other methods was positive.

Dusan Popovic, Tamara Alempijevic, Nada Kovacevic, Milan Spuran, Dragan Tomic, Srdjan Djuranovic, Miodrag Krstic

01.12.2015.

Review Article

Bleeding in late pregnancy

The aim of this paper is to present the incidence of placental abruption and placenta previa at GAO General Hospital N. Pazar like to stress the importance of bleeding in the second trimestreu pregnancy. A retrospective study was conducted at the department of gynecology and obstetrics, ZC Novi Pazar January 2008 December 2012th As the basis of the data, the history and the findings from the protocol konzervtaivno treated surgically and we pacijenata. Analizirali incidence of bleeding compared to the total number of births, maternal age, parity and gestation. During the period of 2008-2012, there were 186 abruption (1.72 %) and 34 placenta previa (0.31%). Within a given period, there were 10778 delivery of which 220 bleeding or 2.03 %. The incidence of placenta previa and ab.placente compared to 84.5% abruption and placenta previa 15.5%. The age of pregnant women who develop bleeding: the highest percentage of bleeding at the age of 26- 31god (43.6%) than in the group of 19-25 years. 82.63 % and the lowest in the group under 18 (3.18) and above 35 years of age (11.3%). Maternal parity. primipara i 92 (41.88%), second child 49 (22.27 %) , third child i 46 (20.91%), fourth child 28 (12.72%). Gestational age at which it contacted the bleeding; 8 to 27 ng (3,645), 28-34 ng 30 (13.63 %) 0.35 to 37 ng 41 (18.64 %), and 37 ng 141 (64%). Method of delivery; caesarean 117 abruption (62%) vaginal delivery 69 (38%). Placenta previa; cesarean section 28 (82.3 %) and 6 vaginal (17.6 %). Any bleeding in the second half of pregnancy should be taken seriously. Prolong pregnancy as possible. You need to pay attention to risk factors: hypertension, gestational diabetes, smoking, previous cesarean section, and in this sense preventive effect on pregnant women.

Ajisa Hajrovic, Samra Hajrovic, Sefcet Hajrovic, Jasmin Nurkovic, Ibrahim Preljevic, Muamer Suljic

01.12.2015.

Review Article

Retroperitoneal liposarcomas: the experience of a tertiary Asian center

Retroperitoneal sarcomas are mesodermic origin and include less than 1% of all malignant tumors. The most frequent histological type of sarcoma are liposarcomas. Most commonly they are located in lower extremitetes while intraabdominal findigs are rare. Early diagnosis is quite challenging because the first symptoms occur only in advanced stages of disease. The gold standard for diagnosing is MSCT. The therapeutic approach is surgical by combining radiation therapy in case of recurrence and excision was not comletly. The chemotherapy is still controversial, and most authors consider that it is not adequate way of treatment. Seventy years old woman was admitted to the department of surgery because of the pain located in theleft half of the abdomen. It lasts for 3 monthsand in recent times became stronger and accompanied by nausea. Stooll and urin were regular . Physical examination revealed painfully formation. Velaues of blood examples were within normal range. US and MSCT of the abdomen were made before operation. MSCT showed retroperitoneal TU formation size 52x35cm. The findings were confirmed during the operation. Tumor weight was 9250g. Histopathological examination showed that it was a low-grade myxoid liposarcoma. One year after surgery, there was a recurrence. The first symptoms of abdominal liposarcoma manifests only in advanced stages of the disease. Radical surgical excision first choice in treatment. If the excsion lines could not be clear radiotherapy should be added.

Goran Ilic, Srdjan Milina, Vladimir Korac, Slavica Popovic

01.12.2014.

Review Article

Multidisciplinary surgical approach in patient with schwannomatosis in the Clinical Hospital Center Zemun

Schwannomas are benign sheat tumors composed of Schwann cells, which are covering peripheral nervs. Althought schwannomas can be found in any localisation, retroperitoneal scheannomas are extremly rare. Multiple schwannomas (neurilemomas) can be part of neurofibromatosis type II, as well as schwannomatosis. Depending on tumor localization, disease symptoms differ. We present a patient with multiple spinal as well as peripheral schwannomas as a part of schwannomatosis. Patient was successfully operated in cooperation between general surgeon and neurosurgeon.

Vuk Aleksic, Vladimir Spica, Radomir Benovic, Milenko Stanic, Tode Dragicevic, Aleksandra Zivkovic, Nenad Zivkovic, Milan Spaic, Velja Milacic

01.12.2014.

Review Article

Case report of lysterious menigitis -Underestimated identity

Listeriosis is an acute infectious disease of the zoonosis, caused by a microorganism Listeria monocytogenes, aerobic or anaerobic microorganism conditionally. The patient had received no department of neurology the clinical picture of hypertensive encephalopathy. Subsequently, the resulting figures are an indication that the sample fluid in isolation L. monocytogenes, the patient is treated with an appropriate antibiotic therapy with a positive outcome. Through illustrate our case quickly progressive neuroinfection we wanted to emphasize the importance of recognizing this now rare and easy to overlook entity, characteristically frequent interventions aging population, newborns, or people who are generally immunocompromised.

Dragoslava Jovanovic

01.12.2014.

Review Article

Gastroschisis -a case report

We are showing this event aimed to highlight the potential for gastroschisis at older mothers over 40 years and not only mothers younger population.The patient M. M, born in 1965, married in 41.years life diagnosed with uterine fibroids two. Three months after her marriage comes naturally to pregnancy. Sonographic findings: One fetus, pelvic presentation, amniotic fluid is optimal in the neck visibly thickened (accentuated nuchal traslucencija), BPD 25 mm, AC 84 mm, 14 mm FL, heart (-) NG / KL 15.2, NG / ultrasound 14.0, the placenta is embedded in the front wall of the uterus contraction. After careful observation in the area of insertion of the umbilical cord can be observed intestinal convolutions freely floating in the amniotic fluid. Grav.ml III IV.HBD ½-15 / 16.FMU. Anomalies foeti obs. Gastroshizis obs. Uterus myomatosus. Consultative decided to terminate the pregnancy GAO HC Novi Pazar. Ekstrahovana Bed, underwent explorative curettage and administered terapija.Fetus a whole with the umbilical cord and placenta sent to PH review. For three weeks the PH finding confirmed gastroschisis and miltipne anomalies. The paper describes the case female patient 41 years old, first pregnancy, in which the early second trimester of fetal gastroschisis diagnosed with absence of fetal heart rate. Pregnancy is consultative decision interrupted without complications.

Ibrahim Preljevic, Sefcet Hajrovic, Muamer Suljic, Nedzib Numanovic, Ajisa Hajrovic, Samra Hajrovic

01.12.2014.

Review Article

Analysis Identification of Victims of Mass Catastrophe in Forensic Dentistry

Natural disaster, such as earthquakes, fires and volcanic eruptions, airline and railway accidents and shipwrecks, as a rule, are very rare, but they always have human victims. Wars are also a form of mass killings of people, but the identification of war victims requires more complex procedures. The most reliable and certain methods used for identification are fingerprints, dental analysis and DNA analysis. Secondary means of identification include a personal description, medical findings, as well as evidence and clothing found on the body. The largest contribution to the identification of the bodies was given by dentists who tried to identify victims with the teeth. Dental identification is an essential procedure that is conducted either independently or as supplement identification. Dentition in process of identifying the victims is used to compare AM (ante-mortem) and PM (post mortem) anthropological characteristics and dental procedures. Today dental identification is unavoidable process, because of its simplicity and because of the speed and economy.

Uros Jovanovic, Zoran Stankovic

01.12.2014.

Review Article

Genetip-fenotip korelacija kod spinalne mišićne atrofi je (SMA)

Spinalna mišićna atrofija (SMA) je autozomno recesivna neuromišćna bolest koju odlikuje progresivna denervacija skeletnih mišića usled propadanja alfa-motoneurona i sledstvena pojava hipotonije, mišićne slabosti, atrofije. Cilj rada je da se pokaže potencijalni uticaj broja kopija SMN2 na razvoj jednog od tri tipa SMA. Ispitivanjem je obuhvaćeno 74 pacijenta oba pola sa kliničkom dijagnozom SMA i to 44 (59.4%) ženskog pola i 30 (40.5%) muškog pola. Pacijenti su klasifikovani u određenu kategoriju SMA (tip 1, 2 ili 3). Glavni kriterijum za klasifikaciju bio je mogućnost samostalnog sedenja/hodanja. Dijagnozu SMA tip 1 imalo je 8 (11.3%) pacijenata, SMA tip 2 27 (38%), dok je SMA tip 3 imalo 36 (50.7%). Homozigotna delecije gena SMN1 bila je zastupljena kod 72/74 (97.2%) pacijenta, dok je kod preostalih detektovana jedna kopija ezgona 7 i 8 SMN1 gena (heterozigotni status), u kombinaciji sa tačkastom mutacijom na drugom alelu. Broj kopija SMN2 gena je bio statistički značajno niži kod SMA tip 1 pacijenta nego kod SMA tip 2 i tip 3 pacijenata (p<0.001). Broj kopija gena SMN2 je u korelaciji sa težinom kliničke slike SMA, što se može koristiti kao jedan od prognostičkih parametara kod ovog obolenja.

Marija Knežević, Jelena Mladenović, Gordana Kovačević, Slavica Ostojić, Jelena Milin-Lazovića, Vedrana Milić-Rašić

01.12.2014.

Review Article

Uporan kašalj kao prvi simptom karcinoma bubrega

Renocelularni karcinom (RCC) je najčešći maligni tumor bubrega kod odraslih. Čini oko 3% adultnih maligniteta i 90-95% neoplazmi bubrežnog porekla. Renocelularni karcinom može biti asimtomatski tokom najvećeg dela svoje evolucije a klasična trijada koja obuhvata lumbalni bol, hematuriju i lumbalnu masu je neuobičajena. RCC se karakteriše čestom pojavom paraneoplastičnog sindroma. Muškarac starosti 46 godina se žalio na uporan kašalj koji je trajao oko godinu dana. Negirao je druge tegobe i nije uzimao blokatore angiotenzin konvertujućeg enzima. Fizikalni nalaz po sistemima je bio u granicama normale. Rezultati laboratorijskih analiza su ukazali na ubrzanu sedimentaciju (SE 92 mm/1.h), leukocitozu i sideropenijsku anemiju (hemoglobin 103 g/L, serumsko gvožđe 4.3 μmol/l). Radiografija srca i pluća i spirometrija su bili uredni. Test na okultno krvarenje u stolici je bio negativan a vrednosti tumor markera su bile u referentnim granicama. Ultrazvuk abdomena je pokazao postojanje tumorske mase duž desnog bubrega. Kompjuterizovana tomografija abdomena je potvrdila postojanje tumorske mase veličine 93x72 mm duž celog desnog bubrega bez znakova invazije okolnih organa. Postavljena je radna dijagnoza renocelularnog karcinoma i izvršena je otvorena desna radikalna nefrektomija. Postoperativni tok je protekao uredno uporni kašalj je nestao 2 dana nakon operacije sa brzim poboljšanjem anemije i normalizacijom SE a uporni kašalj je nestao 2 dana nakon operacije. Tri meseca nakon operacije pacijent nije imao nikakve tegobe niti je bilo znakova rekurencije tumora. Veoma je važno imati u vidu čitav spektar simptoma i znakova kojima se renocelularni karcinom može prezentovati.

Goran Ilic, Marija Klacar, Srdjan Milin, Vladimir Korac, Slavica Popovic

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