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Volume 39, Issue 1, 2025

Online ISSN: 3042-3511

ISSN: 3042-3503

Volume 39 , Issue 1, (2025)

Published: 31.03.2025.

Open Access

Welcome to Issue 39, No. 1 – the first of our two annual publications for this year. Inside, you'll find a curated selection of articles. Start your year with the essential knowledge and perspectives offered in this timely edition

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01.12.2021.

Case Reports

Ulnar nerve schwanomma: Case report

Schwannoma is a slow-growing benign tumor of the peripheral nerve that frequently occurs in the region of the head, neck and spine. We present a 50-year-old male patient diagnosed and operated for schwannoma of the ulnar nerve in the distal part of the left forearm. In the case of a palpable limb mass, one of the possible diagnoses is schwannoma, and since operative technique is somewhat specific with tumor enucleation and internal neurolysis, it is crucial to preoperatively keep in mind schwannoma as a possible diagnosis.

Jovana Prelic, Matija Radojevic, Miljan Mihajlovic, Radmila Culafic, Vuk Aleksic

01.05.2021.

Seminars

Virtuelna kolonografija

Kompjuterizovana kolonografija (KT), poznata i kao virtuelna kolonoskopija je neinvazivna radiološka dijagnostička metoda koja omogućava evaluaciju celog kolona sa ciljem otkrivanja kolorektalnih tumora i klinički značajnih adenomatoznih polipa. U suštini, KT kolonografija predstavlja modifikovani KT pregled kod pacijenta nakon neophodne pripreme creva gde se zatim dobijene slike tumače korišćenjem naprednih tehnika 2D i 3D prikaza1 . Karcinom debelog creva je jedna od najčešćih malignih bolesti kod oba pola i to je drugi je po redu vodeći uzrok smrti zbog malignih bolesti u razvijenim zemljama1 . Skrining i rano otkrivanje raka creva je značajna karika u prevenciji. Konvencionalna kolonoskopija je zlatni standard u dijagnostici i skrning kolorektalnog karcinoma3 .

Kako se kolonoskopija radi pod kontrolom oka, mogu se jasno videti sve, pa i najdiskretnije promene na debelom crevu: zapaljenski procesi, krvarenja, divertikulumi, polipi, benigni i maligni tumori. Virtuelna kolonografija, poznata kao virtuelna kolonoskopija je manje invazivna procedura i radi se pomoću KT skenera, koji propušta rentgenske zrake kroz pacijentov abdomen. Virtuelna kolonoskopija, može da otkrije više neočekivanih tumora od obične kolonoskopije, uključujući i one koji se nalaze van debelog creva. Ova tehnika je mnogo manje invazivna nego standardna kolonoskopija, za koju je obično potrebna anestezija dok lekar vrši pregled debelog creva kolonoskopom tj. savitljivim endoskopskim aparatom4,5.

Osim pogleda na unutrašnjost debelog creva, virtuelna kolonoskopija pregleda celi abdomen i karlicu, te je ovim putem moguće otkriti i tumore izvan debelog creva. Ipak, u praksi se češće koristi standardna, optička kolonoskopija koja je izuzetno pouzdana dijagnostička metoda. Kompjuterizovana tomografska kolonografija ili “virtuelna kolonoskopija” je metod u kojem se koristi tomografska 2D ili 3D slika kolona u cilju ispitivanja strukturnih promena zida creva, intraluminalnih promena ili promena koje sa spoljašnje strane pritiskaju zid creva. Prednost ove metode je što ne zahteva sedaciju, ne nosi rizik od perforacije i zahteva nekoliko minuta za pregled4 . Virtuelna kolonoskopija uz pomoć kompjuterizovane tomografije (KT) ili magnetne rezonance (MR) omogućava dvodimenzionalnu ili trodimenzionalnu sliku debelog creva od najnižeg dela rektuma, pa sve do donjeg kraja tankog creva te ih prikazuje na ekranu. 2D i 3D slike u KT kolonografiji treba da se dopunjuju. 3D interpretacija je korisna za otkrivanje polipa, posebno onih na preklopima zida creva. Sa druge strane, 2D interpretacija pomaže da se potvrdi da li je lezija identifikovana na 3D slici pravi polip ili samo lipoma, adhezivni izmet ili istaknuti nabor. Virtuelna kolonoskopija je manje invazivna od uobičajene optičke kolonoskopije6 .

Vladimir Čotrić, Miloš Dujović, Boris Đukanović

01.12.2021.

Original Articles

The role of the nurse in the treatment of children with hemophilia

The aim of the study was to determine the epidemiological and demographic distribution of patients (age, sex), number of treated children by months, distribution by type of hemophilia, presence of comorbidities, clinical manifestations of hemophilia and severity of hemophilia in relation to age of patients treated for hemophilia. for examination and treatment of hematological and oncological diseases, Institute of Maternal and Child Health “Dr. Vukan Cupic” in the period from January 1, 2020 to December 31, 2020. Hemophilia mainly occurs in the male population and is inherited through the X chromosome (X-linked inheritance). An indirect descriptive method (analysis of medical documentation) was used in the research. Patient disease protocols and case histories were used as a research tool. In relation to age, almost half of the patients (43%) were of school age (age from 7 to 15 years), and in relation to gender, 81% were boys. In relation to the type of hemophilia, most patients had Hemophilia type A was diagnosed in 17 (81%) while Christmas disease (Christmas disease) as it is also called hemophilia type B, hemophilia C (Rosenthal syndrome) and the so-called . von Willebrand’s disease were significantly less common. The most common symptom was bleeding in the joints in 15 patients (71%), and other symptoms such as bleeding into the muscles, hematuria and bleeding in the gastrointestinal tract were less common. The nurse must be specially educated and trained to work with patients with hemophilia.

Slađana Pekmezović, Vojislav Lekic, Ivana P. Joksimovic

01.12.2021.

Original Articles

Chemotherapy: the role of the nurse in care and therapy

The aim of the research was to determine the profile of employed nurses involved in the care of patients receiving chemotherapy and to assess the level of specific education for this type of care. Specialized education, preparation and training are required for oncology nurses who administer chemotherapy and other dangerous anti-cancer drugs to ensure a safe level of care. An observational survey of the survey type was applied, and the results were presented by descriptive statistical methods. The study sample consisted of 20 respondents, nurses and technicians from the Institute of Oncology and Radiology in Belgrade. The research was conducted in the period from May 1 to 20, 2019, at the Institute of Oncology and Radiology in Belgrade. The profile of nurses in our study was that most nurses are traditionally female, with an average age of 36-55 with a high school diploma. Nurses have sufficient knowledge about malignant diseases (65%), 80% are well aware of the side effects of chemotherapy, 55% of nurses provide psychological support to patients with malignant diseases, and 75% assess pain in patients. A slightly higher percentage of 65% of nurses who devote enough time to acquainting patients with their disease and the purpose of treatment. Half of the respondents go to trainings regularly. Based on the results of the research, we can conclude that most nurses have sufficient knowledge about malignant diseases, but the number of those who need additional education is not negligible, to which additional attention must be paid.

Goran Petrovic, Vukasin Delibasic

01.12.2021.

Original Articles

The importance of the work of a nurse in the early detection of persons at increased risk for the development of diabetes at the level of primary health care

The aim of this study was to point out the importance of the work of a nurse in the early detection of persons at increased risk for the development of diabetes at the level of primary health care. DM is a global phenomenon and a major socio-economic and medical problem. The most important tests for the diagnosis of diabetes are the determination of HbA1c and the oral glucose tolerance test (OGTT). The paper conducted a study in the form of analysis of data on examinations performed on 330 patients in 2020 at the Health Center Veliko Gradiste during the implementation of the project “Knowledge to Health” which included screening for early detection of DM type 2 by determining HbA1c-glycosylated hemoglobin and oral glucose tolerance test. The total number of respondents in this study was 330 and the survey was conducted during 2020. The analysis of the study sample showed that more than 184 respondents (55.76%) were female. In relation to age, most respondents were in the age group over 65 (64.54%) years of age in both sexes. This indicates that age (and often associated diseases) is a significant risk factor for type 2 diabetes. Measurement and determination of HbA1c values in both men and women showed that high values were mostly found in people over 65 years of age. The glucose load test in 27 men (oral glucose tolerance test - OGTT test) showed that normal tolerance exists in 10 men over the age of 65, w h ile 3 men over the age of 65 have a high risk of developing diabetes. Diabetes mellitus was determined by a glucose load test in 4 women ove r the age of 65, then in 1 woman aged 55-64, as well as in 2 women aged 45-54. One of the basic tasks of nurses is to conduct health education work with patients, give advice for successf u l treatment and care, and if done properly, it c an reduce one of the most important public health problems of modern society.

Vesovic Dusan, Anita Nestorovic

01.12.2021.

Case Reports

Acute coronary syndrome in apical hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy in the absence of abnormal cardiac loading conditions. Apical hypertrophic cardiomyopathy (Yamaguchi syndrome) is a relatively rare HCM phenotype. It is characterized by apical left ventricular hypertrophy, often with the absence of left ventricular outflow tract obstruction. In patients with HCM symptoms of angina are quite common, mostly due to microvascular dysfunction or oxygen supply demand mismatch. Here we present a case of apical hypertrophic cardiomyopathy with concomitant severe coronary artery disease.

Radosava Cvjetan, Ivona Vranić, Predrag Miličević, Srđan Kafedžić, Nataša Rakonjac

01.12.2021.

Case Reports

Pulmonary valve blood cyst in an adult patient: a case report

In this paper, we describe the case of an adult male with a pulmonary valve blood cyst. Blood cysts are benign primary heart tumors, common in neonates, but very rare in adults, mostly asymptomatic, and detected incidentally. Ultrasound (transthoracic transephophageal echocardiography) is crucial in detecting lesion, with the help of other diagnostic methods (MRI, CT). Further treatment, conservative or surgical, depends on the effect of the cyst on heart function. Although the diagnosis of cardiac lesions using routine imaging is available, definitive diagnosis is possible only by pathohistological and immunohistochemical analysis of the surgical sample.

Marija M Milinkovic, Vesna Bozic, Svetislav Tatic, Mladen Kocica

02.05.2020.

Original Articles

Hospital mortality of patients with acute myocardial infarction in the first year of the implementation of the primary PCI program in the Clinical-Hospital Center Zemun

Acute coronary syndrome is common term for various clinical conditions such as unstable angina (UA), myocardial infarction without ST segment elevation (NSTEMI) and myocardial infarction with ST segment elevation (STEMI). ACS is one of the leading cause of morbidity and mortality worldwide. The most serious manifestation of this syndrome is STEMI. The main goal of treatment is rapid restoration of blood flow in the infarct related artery. This can be achieved either with conservative (thrombolysis) or invasive (primary or rescue percutaneous coronary intervention – pPCI or rPCI) approach. Based on the data from varoius registries, the rate of complications of these type of interventions is low and they can be safely performed in centers without on site cardiac surgery. The main goal of this paper is to assess in-hospital mortality as well as demographic, clinical and angiographic characteristics of patients with STEMI treated in cardiac catheteterisation lab in the Clinical Hospital Center Zemun during the first year of implementation of pPCI program. The study included 284 consecutive STEMI patients. Total in-hospital mortality was 4.9% and, depending of the severity of heart failure at admission (Killip/Kimball class), the highest mortality was in cardiogenic shock (54,5%). The most common intrahospital complications were complicated infections unrelated to the pPCI procedure (3.5%), vascular complications (2.8%) and early stent thrombosis (2.1%). No patient was reffered to emergency cardiac surgery due to unsuccesfull or complicated pPCI procedure. Our study showed that performing pPCI during the first year of the implementation of pPCI program in the center without on-site cardiac surgery support was safe end effective and resulted in low in-hospital mortality.

Srdjan Kafedzic, Bojan Ilisic, Milivoje Cerovic, Aleksandar Aleksic, Ivica Nikolajevic, Zoran Stajic, Dusan Milicevic, Ivan Ilic, Gojko Obradovic, Alja Vlahovic-Stipac, Milos Panic, Predrag Milicevic, Dragan Petrovic, Biljana Vasic, Nikolina Nedic, Biljana Putnikovic, Aleksandar N. Neskovic

01.01.2020.

Case Reports

Breast cancer associated with pregnancy: Is magnetic resonance imaging indicated?

Pregnancy-associated breast cancer is defined as breast cancer diagnosed during pregnancy or in the first postpartum year. High hormons level (estrogen, progesteron and prolactin) during this specific period make structural changes, increase breast volume and density and make the diagnosis often very difficult. We present the case of 38 old women, who noted a painless breast mass during first month of breastfeeding.

Svetlana Kocic, Nenad Janeski, Natasa Rakonjac

02.05.2020.

Original Articles

The role of pelvic lymphadenectomy in the treatment of endometrial cancer

This study aimed to evaluate the degree of involvement and infiltration of the pelvic lymph glands in endometrial cancer. The retrospective study included patients who were diagnosed with endometrial cancer after exploratory curettage, and who were then referred for surgical treatment with partial or total pelvic lymphadenectomy. We analyzed 99 patients who met the inclusion criteria. Pelvic lymphadenectomy is the treatment of choice in patients with medium and high risk endometrial cancer for disease recurrence. Given the importance of the evaluated issue, it is necessary to perform randomized studies to examine the therapeutic effect of pelvic and paraaortic lymphadenectomy, especially in patients at medium and high risk for recurrence of endometrial cancer.

Mirko Mackic, Stefan Ivanovic, Milan Perovic, Ninoslav Dejanovic

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