Nonspeci¿ c interstitial pneumonia is a type of idiopathic interstitial pneumonia. By de¿ nition, the cases of nonspeci¿ c interstitial pneumonia are those which cannot be classi¿ ed as any other type of interstitial pneumonia. The Material of the investigation included 12 transbronchial biopsy lung samples. The quantity, structure and distribution of speci¿ c cellular elements were determined semiquantitatively, recognizing three levels of the lesions’ intensity: mild/ poor, moderate, and intense/abundant. The interalveolar septa were most frequently moderately thickened (50% of the cases) due to the presence of inÀ ammatory cells and multiplied connective. Of the inÀ ammatory cells, lymphocytes were most common and greatest in quantity (abundant, moderate and poor in 4, 5, and 3 cases respectively), followed by plasma cells and macrophages. The septal connective was moderately and mildly multiplied in 2 and 4 cases respectively. The lumen of the alveoli was in¿ ltrated by lymphocytes and macrophages, while poor peribronchial and perivascular lymphocyte in¿ ltrates were most commonly found. The interalveolar septa were most frequently moderately thickened due to the presence of chronic inÀ ammatory cells, predominantly lymphocytes, as well as to mildly-to-moderately multiplied connective. The lymphocytes usually permeated the septa diffusely. Bronchiolar and blood vessel ¿ ndings were nonspeci¿ c.

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.