According to the relevant investigations during past decade there is a great increase of malignant skin tumors. By this research we tried to investigate this hypothesis in domestic population and present complicated reconstructive procedure. In this research were included 591 patients with melanomas and carcinomas of head and neck, who were surgically treated at our clinic from 2000. to 2010. Results of this research showed that 50 patients had melanoma and 541 carcinomas of skin. We have found that men are four times more affected by skin facial carcinomas than women. 62% patients with squamous cell carcinoma, who were primary surgically treated, survived more than 5 years. On other hand, 85% patients with basal cell carcinomas survived more than 5 years.

Sposobnost organizma da zaustavi krvarenje iz oštećenog krvnog suda je neophoda za preživljavanje pacijenta.Isto tako,veliki uticaj ima i sposobnost organizma u regulisanju različitih procesa u koagulaciji krvi,čime
se može sprečiti nastanak tromboza i mogućih fatalnih posledica. U zdravom organizmu postoji ravnoteža
prokoagulantnih i antikoagulantnih faktora hemostaze i pod normalnim okolnostima sistem funkcioniše u korist prevage antikoagulacije Hirurške procedure u tretmanu bolesti ginekološkh organa nose veliki rizik za
nastanak dubokih venskih tromboza , imajući u vidu anatomske odnose u maloj karlici i bogatu vaskularizaciju obturatornih i ilijačnih jama.Standarna terapijska doza heparina niske molekulske mase (LMWH) sa ciljem prevencije nastanka venskih tromboza, a u slučajevima blagog i umerenog rizika je 3.000-5.000U/24
h.U svim slučajevima visokog rizika, doza niskomolekulskog heparina se može udvostručiti . Veća sklonost
ka nastanku dubokih venskih tromboza u svakoj hirurškoj proceduri u maloj karlici naročito kod ženske populacije, stavlja primenu heparina niske molekulske mase kao primarni cilj u prevenciji eventualne tromboembolijske bolesti.

Congenital heart disease is the most important cause of infant mortality. Abnormalities of the heart and great arteries are the most common congenital defects. Congenital heart disease is often fallow by extracardiac malformations. Many studies revailed positive impact of prenatal diagnosis and timelly treatment on pre-operative condition and outcome of surgery and long term prognosis. Neverthelles, structural cardiac anomalies were also among the most frequently missed abnormalities by prenatal ultrasonography at mid-trimester scan. The 4-chamber view has a Detection Rate of 6-50%, with a reasonable figure of 20% in community setting screening programs. The addition of the outflow determines a significant increase of the Detection Rate which, in most studies, ranges 20-40%. The three-vessel view allows to detect major abnormalities of the arches, the neck vessels and the thymus. The prenatal detection of specific types of congenital heart disease, such as Transposition of great arteries, Hypoplastic left heart syndrome, Tetralogy Fallot, seems to have a significant impact on survival, hospital stay and pre-operative conditions of the affected neonates. Hence, fetal cardiac screening is a must for all health professionals involved in prenatal diagnosis.

Tuberculous peritonitis is a specific inflammatory disease of the peritoneum, rare in developed countries, often in developing countries. Symptoms usually have a chronic character and appearance of ascites is often the initial symptom of the disease. Symptomatology may not be typical. It occurs most often anorexia, weight loss, abdominal pain and subfebrile temperature Presented 23-year-old patient, after elective surgery on the right inguinal hernia, when the changes in the peritoneum and omentum were observed and 2l of ascites were evacuated, was admitted to Hospital for emergency surgery, Clinical Centre of Serbia, Belgrade for further diagnostic and therapeutic treatment. The patient noted occasional mild abdominal pain, bloating, fatigue and general weakness. Chest radiography showed a small pleural effusion in the right and laminar athelectasis in the lower right lung field. On performed EHO and MSCT of the abdomen is visible easily enlarged liver, with a discrete dilation of intrahepatic bile ducts, gallbladder with calculuses. Portal and spleen vein dilated, enlarged spleen. Right subphrenic and interintestinally present clear liquid. Other findings in order. Exploratory laparotomy was perfomed. Histopathological examination, of the slices of the peritoneum, confirmed changes typical for tuberculous peritonitis.

The overall survival rate in infants affected by congenital heart disease remains low. The poor outcome may be related to the increased association with extracardiac anomalies and aneupoloidy. Since most types of CHD are now amenable to surgery, it is essential that any fetus with congenital structural heart defect should be completely evaluated, noting in particular congenital extracardiac defects which may adversely affect the prognosis. Noncardiac malformations have been reported to occur in up to 50% of patients with congenital heart disease. The combination of cardiac anomalies with other organ abnormalities appears in genetic syndromes and after exposure to environmental factors. Fetuses with prenatally diagnosed cardiac malformations need to have offer structural abnormalities ruled out. They should be evaluated thoroughly by ultrasound exam, because the detection of an extracardiac anomaly may dramatically affect prognosis. Also, fetuses in which an extracardiac anomaly or chromosome abnormality is diagnosed deserve a complete evolution with full fetal echocardiography. Fetal caryotype analysis should be performed since the risk of aneuploidy approaches 40% in cases of prenatally diagnosed CHD.

Although the first balloon dilation of aortic stenotičnog valve in the fetus was performed successfully as early as 1989th , the fetal cardiac intervention procedures are still in experimental medicine and performed in a few centers in the world. Interventional cardiology procedures at this time in the application of the fetuses with aortic stenosis, fetuses with stenosis / atresia of the pulmonary artery and hypoplasia of fetuses with left ventricle and restrictive međupretkomorskim hole.

Diskus hernija je bolest međupršljenskog diska kičmenog stuba koja nastaje kao posledica prolapsa (hernijacije) i prodora želatinoznog jezgra međupršljenskog diska u međupršljenske otvore (lat. foramina intervertebrales) gde vrši pritisak na korenove spinalnih živaca, a ponekad i centralno u spinalni kanal i prostor u kome se nalaze kičmena moždina i kauda ekvina koje takođe komprimuje. Uzrok diskus hernije je često fizičko preopterećenje već postojećih oštećenja međupršljenskog diska, herniacija diska, reumatične i zapaljenjske bolesti, ali i bezuzročna koja nastaje bez uticaja ikakvih spoljnih uzroka. Simptomi diskus hernije su: jak bol, najčešće lokalizovan u leđima i udovima, iradijacija bola, ukočenost i ponekad paraliza. Lečenje je konzervativno, a kod težih slučajeva i operativno.

Improved methods of early detection and modern therapeutic protocols for malignant diseases led to better survival and increased ratio of cured patients diagnosed for malignances. Cancer survivors are population with increased risk not only for recurrence of the disease but for new primaries and other chronic conditions. Life-style factors, such as nutrition, physical activity and weight management, play key role in preventing these risk factors. Patients in each phase of malignant disease have specific nutritional needs and location of the primary disease and therapeutic modalities additionally modify these needs.

Tracking of anatomical and functional results obtained after non-surgical treatment of the distal radius including 51 patients. Tracking of the results was based upon Anatomical Score System and Gartland-Werley Score System. The final numerical results obtained through Anatomical Score were the following:excellent in 12 cases (23.52%), good in 30 cases (58.82%), satisfactory in 8 cases (15.68%), dissatisfactory in 1 case (1.96%). According to the Gartland-Werley Score System, the final results included: excellent in 19 cases (37.25%), good in 24 cases (47.00%), satisfactory in 7 cases (13.72%), dissatisfactory in 1 case (1.96%). This work also presents correlation between Residual Deformity score, Subjective Hardship score and Objective dysfunction, with the results obtained by Anatomical score and Gartland-Werley total score. The possibility of dissatisfactory results obtained by radiological screening followed by dissatisfactory outcome is described in literature; however, dissatisfactory screening results could be found in up to 31.7% of cases with satisfactory clinical findings. Our work records 15.7% of the latter cases. We might say that non-surgical treatment is not to be accepted as the only and exclusive approach to distal radius fracture. Thus, proper evaluation is mandatory.

The present study is performed to determine whether retroperitoneal lymphadenectomy (RPLA) perioperative mortality (PM) rates reported from center of excellence [Indiana University: 0% for primary and 0.8% for postchemotherapy (PC) RPLA] are applicable to institution at large. Between 1975 and 2005, 327 assessable patients with nonseminomatous testicular tumors (NSTT) were treated with RPLA: primary in 134 (41%) and PC-RPLA in 193 (59%) patients. The observed PM rates were stratified according to age, clinical stage (CS) and type of RPLA. The median age at RPLA was 28 years (range 16-54) : < 29 years in 194 (56.3%), 30-39 years in 90 (30.3%) and > 40 years in 44 (13.4%) patients. Of 327 RPLA patients, 81 (27.8%) were performed for localized (CS-I), 179 (54.7%) for regional (CS-II) and 57 (17.5%) for metastatic (CS-III) disease. Ten (3.1%) patients died during initial 90 days after RPLA: 1 patient from pulmonary embolism, 2 of chemotherapyrelated toxicity and 7 of progressive disease due to preoperative worse prognostic factors. Of the entire cohort 30, 60 and 90-day PM rate was 0.3%, 1.0% and 1.3%, respectively. PM rate increase with increasing age: < 39 years 0%, 30-39 years 5.0% and > 40 years 9.3% (x2 trend test, P=0.002). PM rate also increased with CS: 0% localized, 2.8% for regional and 8.8% for metastatic disease (x2 trend test, p<0.001). PM rate at primary and PC-RPLA was increased with CS: 0% localized, 2.8% for regional and 8.8% for metastatic disease (x2 trend test, p<0.001). PM rate at primary and PC-RPLA was 0.7% and 3.1% 9P<0.001). RPLA was associated with virtually no or low (2.8%) PM rate in patients with localized and regional disease, respectively. In contrast, the PM rate of 8.8% for patients with distant metastases and group > 40 years of age (9.3%) implies that RPLA for these patients should be performed at centers of excellence, with intent of reducing PM rate.