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Volume 39, Issue 1, 2025

Online ISSN: 3042-3511

ISSN: 3042-3503

Volume 39 , Issue 1, (2025)

Published: 31.03.2025.

Open Access

Welcome to Issue 39, No. 1 – the first of our two annual publications for this year. Inside, you'll find a curated selection of articles. Start your year with the essential knowledge and perspectives offered in this timely edition

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01.12.2013.

Review Article

Trisomy 13 detection in the first trimester of pregnancy using a chromosome‐selective cell‐free <scp>DNA</scp> analysis method

Trisomy 13 (Sy Patau) is a clinically severe entity. 85% of the patients do not survive beyond one year, and most children die before completing six months of age. We report a female child, 30 day old, white, the third child of a non-consanguineous couple, who presented trisomy 13. The child was born at term, from a vaginal delivery, weighing 3200 g. The second day of life the development of respiratory distress translated ino KBC Kragujevac (release list no.29623). The initial clinical examination detected shisis primariy and secunday palate, ASD, stenosis rami AP, polidactily pedis dextri, microcornea and microftalmia. After 27 days of hospitalization in KBC Kragujevac, transferred to the Institute for mother and child New Belgrade, where he died after three days of receipt. During hospitalization blood samples were taken for determination of kariotip. Parents are advised that in case of subsequent pregnancies occur in the genetic counseling of the Institute for prenatal diagnosis.

Ajiša Hajrović, Ibrahim Preljević, Šefćet Hajrović, Jasmin Nurković, Nebojša Milosavljević, Samra Hajrović

01.12.2013.

Review Article

Pseudocyst of the spleen-report of two cases

Cysts of the spleen are rare disease that affects the spleen. They are divided into primary and secondary in relation to the etiology and histopathology. We report two young patients of a boy aged 16 and a girl of 15 godina. Ultrasonography and CT of the abdomen showed a large cystic mass in the spleen unclear origin. On laparotomy for both the patient was found a large cyst that reached to the upper pole of the spleen and required total splenectomy. Histopathology showed fibrous cyst wall with areas of hyaline degeneration below which there is significant blood kongstion.Etipatogenesis and different modalities of treatment for cysts of the spleen are questionable. Although pseudocysts of the spleen are rare, they must be considered in the differential diagnosis of abdominal masses in the upper abdomen in young adolescents.

Šefćet Hajrović, Ibrahim Preljević, Ajiša Hajrović, Jasmin Nurković, Nebojša Milosavljević, Samra Hajrović, Emina Preljević

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