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Volume 40, Issue 1, 2026

Online ISSN: 3042-3511

ISSN: 3042-3503

Volume 40 , Issue 1, (2026)

Published: 31.05.2026.

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31.05.2026.

Original Article

DIAGNOSTIC SIGNIFICANCE OF COMPUTED TOMOGRAPHY IN THE PREOPERATIVE ASSESSMENT OF T AND N STAGES OF COLORECTAL CARCINOMA

Introduction: Preoperative imaging staging of colorectal cancer is essential for optimal therapeutic planning. Multidetector computed tomography (MDCT) is the standard imaging modality for initial staging; however, its diagnostic accuracy in assessing tumor depth and nodal status remains debated.

Objective: To evaluate the diagnostic accuracy of MDCT in preoperative T and N staging of colorectal cancer by comparison with operative and histopathological findings as the reference standard.

Methods: A retrospective analysis was conducted in 63 patients with histopathologically confirmed colorectal cancer who underwent preoperative contrast-enhanced CT of the abdomen and pelvis. CT-based assessment of T and N stages was compared with operative and histopathological findings. Agreement was evaluated using appropriate statistical methods.

Results: MDCT demonstrated the highest diagnostic accuracy in identifying T3 tumors. Overall agreement between CT and histopathological findings for individual T stages was low but statistically significant (Kappa = 0.166; p = 0.049), with a predominant tendency toward understaging. When T stages were grouped into low (T1–T2) and high (T3–T4) categories, diagnostic accuracy reached 71.4%. Nodal staging with morphological status showed high agreement in binaryclassification  (Kappa = 0.682; p < 0.001), but limited reliability acording to size of lymph node

Conclusion: MDCT shows good diagnostic performance in preoperative T staging of colorectal cancer, particularly in advanced stages, while nodal staging remains limited and requires cautious interpretation.

Nataša Rakonjac, Tamara Gligorić, Vladimir Čotrić, Jelena Čotrić, Mihajlo Korać, Radomir Kovačević, Jelena Filipović, Aleksandar Mandarić, Darko Grujić, Dejana Senji, Jovana Latov, Vesna Prodanović, Milica Lakićević, Mirjana Tubić Milojević, Predrag Popović, Mladen Jovanović

01.12.2021.

Case Report

Acute coronary syndrome in apical hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy in the absence of abnormal cardiac loading conditions. Apical hypertrophic cardiomyopathy (Yamaguchi syndrome) is a relatively rare HCM phenotype. It is characterized by apical left ventricular hypertrophy, often with the absence of left ventricular outflow tract obstruction. In patients with HCM symptoms of angina are quite common, mostly due to microvascular dysfunction or oxygen supply demand mismatch. Here we present a case of apical hypertrophic cardiomyopathy with concomitant severe coronary artery disease.

Radosava Cvjetan, Ivona Vranić, Predrag Miličević, Srđan Kafedžić, Nataša Rakonjac

01.12.2017.

Review Article

Atipična renalna cista koja imitira bubrežni karcinom: prikaz slučaja

Atipične ciste bubrega klasifikovane kaoBosniak III ili IV sususpektne na malignitet ali je u nekimslučajevima teško uspostaviti pravu dijagnozu uprkos savremenim radiološkim metodama i predložiti odgovarajući terapijski pristup. Evaluiramo slučaj komplikovane hemoragične bubrežne ciste kod 73 –godina starog pacijenta. Pacijent je primljen u našu bolnicu na dalju evaluaciju zbog nespecifičnih bolova u leđima i trbuhu i zbog hroničnih urinarnih infekcija. Ultrazvukom su verifikovane bilateralne ciste bubrega od kojih neke sa gustim sadržajem. Nakon CT pregleda jedna od tih cista je klasifikovana kao Bosniak II F, zbog diskretne opacifikacije zida ciste u jednom segmentu, dok je MR nalaz ukazao na suspektnu malignu leziju, pri čemu je opisana restrikcija difuzije intraluminalno, što ukazuje na prisustvo solidnog dela, te je pacijent nefrektomisan. Patohistološki pregled je verifikovao inflamiranu hemoragičnu cistu bez prisustva malignih ćelija. Atipična cista bubrega može odgovarati komplikovanoj cisti sa infekcijom ili krvarenjem, ali takođe i cističnom tumoru. Radiološki pregled često nije dovoljan za jasnu diferencijaciju. Lažno negativne biopsije kod cističnih promena su vrlo izvesne i često je neophodno izvršiti hiruršku intervenciju za preciznu dijagnozu.

Nataša Rakonjac, Nenad Janeski, Svetlana Kocić, Aleksandra Cvijović, Jovana Latov-Bešić, Vladimir Čotrić, Aleksandar Mandarić, Mirko Vasilski

01.12.2017.

Case Report

Extrauterine mesenteric leiomyoma – case report

We present the case of a 46-year-old patient diagnosed with a large solid tumor localized in the right mesentery, and due to the mesenteric position and tumor structure, diagnostic suspicion of GIST was proposal as the most frequent tumor lesion of this localization. After a few days, the patient was discharged from the hospital without postoperative complication, in further follow-up without relapse.

Natasa Rakonjac, Nenad Janeski, Aleksandra Cvijovic, Jovana Latov Bešić, Mirjana Tubić, Svetlana Kočić, Vuk Andrejević

01.12.2016.

Review Article

Extrauterine mesenteric leiomyomacase report

We present the case of a 46-year-old patient diagnosed with a large solid tumor localized in the right mesentery, and due to the mesenteric position and tumor structure, diagnostic suspicion of GIST was proposal as the most frequent tumor lesion of this localization. After a few days, the patient was discharged from the hospital without postoperative complication, in further follow-up without relapse.

Nataša Rakonjac, Nenad Janeski, Vladimir Čotrić, Aleksandra Cvijović, Jovana Latov-Bešić, Mirjana Tubić, Svetlana Kocić, Vuk Andrejević

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