Introduction: Endometrial cancer is one of the most common malignant tumors of the female reproductive system. PCOS is a complex endocrinological disease of women of reproductive period.Conservative therapy implies a safe oncological outcome while preserving reproductive function.

Methods: This study is a cross-sectional clinical study conducted at Unirvesity Clinical Center of Serbia,Clinic for Gynecology and Obstetrics in the period from 2012 to 2024. The study included 62 patients who were between 23 and 45. The study included patients who were consecutively examined and treated conservatively for endometrial hyperplasia or endometrial cancer. Statistical analysis included methods of descriptive and analytical statistics.

Results: The results obtained in our study indicate that by evaluating the endocrinological status in patients with endometrial cancer, appropriate hygienic and dietary regimen, application of conservative therapy as well as psychosocial support to the patient. It is possible to obtain good therapeutic outcomes while preserving fertility in patients with endometrial cancer.

Conclusion: This study highlights the importance of alternative conservative treatment for endometrial cancer, especially in younger women with well-differentiated, early-stage endometrioid cancer