Current issue
Volume 40, Issue 1, 2026
Online ISSN: 3042-3511
ISSN: 3042-3503
Volume 40 , Issue 1, (2026)
Published: 31.05.2026.
Open Access
All issues
Contents
31.05.2026.
Case Report
HYPERBARIC OXYGEN THERAPY IN THE TREATMENT OF A NON-HEALING WOUND AFTER AMPUTATION IN A PATIENT WITH DIABETES – CASE REPORT
Diabetic foot syndrome represents one of the most severe complications of diabetes and is the leading cause of non-traumatic amputations. Wound healing is often impaired due to hypoxia, infection, and vascular changes. Hyperbaric oxygen therapy (HBOT) is used as an adjuvant method in the treatment of chronic wounds.
A 57-year-old patient is presented with a non-healing wound following amputation of the left foot due to gangrene associated with diabetic foot syndrome. After standard therapy and the introduction of HBOT (25 sessions at 2 ATA), a significant reduction in wound size and the development of granulation tissue were observed. Six months later, due to persistence of a smaller wound, an additional cycle of therapy was administered.
HBOT improves tissue oxygenation, stimulates angiogenesis, enhances the bactericidal activity of leukocytes, and accelerates tissue repair. When combined with standard treatment measures, it can significantly improve outcomes in patients with diabetic foot syndrome.
HBOT represents an effective adjuvant therapy in the treatment of chronic wounds in diabetic foot syndrome and may contribute to reducing the need for further amputations.
Tatjana Opačić, Danijela Nešović, Anja Zec, Davorka Milačić, Miloš Vojinović
01.12.2013.
Review Article
ORIGINALNI RADOVI CASE REPORTS Mouth opening scope in the patients with systemic sclerosis -Simultaneously application of a hyperbaric oxygenation and physical therapy
During our perennial work with patients with systemic sclerosis we noticed that after the therapy of hyperbaric oxygenation (HBOt) they were able to their mouths open more easily. This treatment effect became visible when we started treating our patients with physical therapy. In order to find out whether this was patients’ subjective impression or an objective increase, we decided to keep the track of changes in mouth circumference before and after combined therapy of hyperbaric oxygenation and physical therapy. We treated the patients with ten HBO treatments at 2.0 ATA. Physical therapy lasted for ten days. First, the patients went to phototherapy with infrared rays (Solux lamp) for 15 minutes, at 40 cm intervals, perpendicularly, and then they went to kinesitherapy for mimic musculature in front of a mirror. Measurements before and after the therapy have shown a statistically significant difference and proved that the combination of HBO therapy and physical therapy has its place in treating these patients.
Davorka Milacic, Koviljka Cobeljic, Radmilo Isakovic